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10.14218/JCTH.2014.00024

http://scihub22266oqcxt.onion/10.14218/JCTH.2014.00024
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C4521232!4521232!26357630
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suck abstract from ncbi


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pmid26357630      J+Clin+Transl+Hepatol 2014 ; 2 (4): 266-84
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  • Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis: a Review Featuring a Women s Health Perspective #MMPMID26357630
  • Marchioni Beery RM; Vaziri H; Forouhar F
  • J Clin Transl Hepatol 2014[Dec]; 2 (4): 266-84 PMID26357630show ga
  • Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are two major types of chronic cholestatic liver disease. Each disorder has distinguishing features and variable progression, but both may ultimately result in cirrhosis and hepatic failure. The following offers a review of PBC and PSC, beginning with a general overview of disease etiology, pathogenesis, diagnosis, clinical features, natural course, and treatment. In addition to commonly associated manifestations of fatigue, pruritus, and fat-soluble vitamin deficiency, select disease-related topics pertaining to women's health are discussed including metabolic bone disease, hyperlipidemia and cardiovascular risk, and pregnancy-related issues influencing maternal disease course and birth outcomes. This comprehensive review of PBC and PSC highlights some unique clinical considerations in the care of female patients with cholestatic liver disease.
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