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10.1007/s40429-015-0046-y http://scihub22266oqcxt.onion/10.1007/s40429-015-0046-y C4520241!4520241!26236574     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Addict+Rep 2015 ; 2 (1): 76-90 Nephropedia Template TP {{tp|p=26236574|t=2015. Endophenotypes for Alcohol Use Disorder: An Update on the Field |pdf=|usr=}}{{26236574}} gab.com Text Endophenotypes for Alcohol Use Disorder: An Update on the Field JO: Curr Addict Rep http://www.kidney.de/pget.php?&tw=1&pmid=26236574 #FOAvip The endophenotype concept was first proposed as a strategy to use (purportedly) genetically simpler phenotypes in gene identification studies for psychiatric disorders, and is distinct from the closely related concept of intermediate phenotypes. In the area of alcohol use disorder (AUD) research, two candidate endophenotypes have produced replicable genetic associations: level of response to alcohol and neurophysiology markers (e.g., event-related oscillations and event-related potentials). Additional candidate endophenotypes from the cognitive, sensory, and neuroimaging literatures show promise, although more evidence is needed to fully evaluate their potential utility. Translational approaches to AUD endophenotypes have helped characterize the underlying neurobiology and genetics of AUD endophenotypes and identified relevant pharmacological interventions. Future research that capitalizes on the polygenic nature of endophenotypes and emphasizes endophenotypes that may change across development will enhance the usefulness of this concept to understand the genetically-influenced pathways toward AUD. Twit Text FOAVip Endophenotypes for Alcohol Use Disorder: An Update on the Field ????Curr Addict Rep http://www.kidney.de/pget.php?&tw=1&pmid=26236574 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26236574 #FOAvip English Wikipedia <ref>{{Cite pmid|26236574}}</ref> Endophenotypes for Alcohol Use Disorder: An Update on the Field #MMPMID26236574 Salvatore JE; Gottesman II; Dick DM Curr Addict Rep 2015[Mar]; 2 (1): 76-90 PMID26236574show ga The endophenotype concept was first proposed as a strategy to use (purportedly) genetically simpler phenotypes in gene identification studies for psychiatric disorders, and is distinct from the closely related concept of intermediate phenotypes. In the area of alcohol use disorder (AUD) research, two candidate endophenotypes have produced replicable genetic associations: level of response to alcohol and neurophysiology markers (e.g., event-related oscillations and event-related potentials). Additional candidate endophenotypes from the cognitive, sensory, and neuroimaging literatures show promise, although more evidence is needed to fully evaluate their potential utility. Translational approaches to AUD endophenotypes have helped characterize the underlying neurobiology and genetics of AUD endophenotypes and identified relevant pharmacological interventions. Future research that capitalizes on the polygenic nature of endophenotypes and emphasizes endophenotypes that may change across development will enhance the usefulness of this concept to understand the genetically-influenced pathways toward AUD. äEndophenotypes for Alcohol Use Disorder: An Update on the Field (epmc).pdf DeepDyve Pubget Overpricing