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10.3390/v7072810 http://scihub22266oqcxt.onion/10.3390/v7072810 C4517139!4517139!26205405     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26205405&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Viruses 2015 ; 7 (7): 4093-118 Nephropedia Template TP {{tp|p=26205405|t=2015. Exosomes: Implications in HIV-1 Pathogenesis |pdf=|usr=}}{{26205405}} gab.com Text Exosomes: Implications in HIV-1 Pathogenesis JO: Viruses http://www.kidney.de/pget.php?&tw=1&pmid=26205405 #FOAvip Exosomes are membranous nanovesicles of endocytic origin that carry host and pathogen derived genomic, proteomic, and lipid cargos. Exosomes are secreted by most cell types into the extracellular milieu and are subsequently internalized by recipient cells. Upon internalization, exosomes condition recipient cells by donating their cargos and/or activating various signal transduction pathways, consequently regulating physiological and pathophysiological processes. The role of exosomes in viral pathogenesis, especially human immunodeficiency virus type 1 [HIV-1] is beginning to unravel. Recent research reports suggest that exosomes from various sources play important but different roles in the pathogenesis of HIV-1. From these reports, it appears that the source of exosomes is the defining factor for the exosomal effect on HIV-1. In this review, we will describe how HIV-1 infection is modulated by exosomes and in turn how exosomes are targeted by HIV-1 factors. Finally, we will discuss potentially emerging therapeutic options based on exosomal cargos that may have promise in preventing HIV-1 transmission. Twit Text FOAVip Exosomes: Implications in HIV-1 Pathogenesis ????Viruses http://www.kidney.de/pget.php?&tw=1&pmid=26205405 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26205405 #FOAvip English Wikipedia <ref>{{Cite pmid|26205405}}</ref> Exosomes: Implications in HIV-1 Pathogenesis #MMPMID26205405 Madison MN; Okeoma CM Viruses 2015[Jul]; 7 (7): 4093-118 PMID26205405show ga Exosomes are membranous nanovesicles of endocytic origin that carry host and pathogen derived genomic, proteomic, and lipid cargos. Exosomes are secreted by most cell types into the extracellular milieu and are subsequently internalized by recipient cells. Upon internalization, exosomes condition recipient cells by donating their cargos and/or activating various signal transduction pathways, consequently regulating physiological and pathophysiological processes. The role of exosomes in viral pathogenesis, especially human immunodeficiency virus type 1 [HIV-1] is beginning to unravel. Recent research reports suggest that exosomes from various sources play important but different roles in the pathogenesis of HIV-1. From these reports, it appears that the source of exosomes is the defining factor for the exosomal effect on HIV-1. In this review, we will describe how HIV-1 infection is modulated by exosomes and in turn how exosomes are targeted by HIV-1 factors. Finally, we will discuss potentially emerging therapeutic options based on exosomal cargos that may have promise in preventing HIV-1 transmission. äExosomes: Implications in HIV-1 Pathogenesis (epmc).pdf DeepDyve Pubget Overpricing