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2015 ; 10
(7
): e0133993
Nephropedia Template TP
gab.com Text
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English Wikipedia
Gender Differences in the Symptoms, Signs, Disease History, Lesion Position and
Pathophysiology in Patients with Pulmonary Embolism
#MMPMID26208352
Deng X
; Li Y
; Zhou L
; Liu C
; Liu M
; Ding N
; Shao J
PLoS One
2015[]; 10
(7
): e0133993
PMID26208352
show ga
Advances in research relating to pulmonary embolisms (PE) can assist physicians
in selecting the best management strategies for PE patients. However, the
symptoms, signs, disease history, lesion position and pathophysiology linked to
different genders in patients with PE have rarely been evaluated. One hundred and
forty-nine PE patients (73 males and 76 females) were sequentially recruited to
this study over the last five years whilst attending our Emergency Department.
Data relating to the symptoms, signs, disease history, biochemical testing,
cardiac electrophysiology, imaging detection, treatment and outcome were
collected and the gender differences were analyzed. We found that embolisms
occurred significantly more frequently in the right lung (89.7%) than in the left
lung (42.6%). The presence of dyspnea, the number of patients presenting with
tumors, the number of patients with chronic pulmonary disease, those with emboli
in the right pulmonary artery and emboli in the right lung, as well as the
average systolic and diastolic blood pressure were: 78.1%, 15.1%, 31.5%, 32.9%,
94.5%, 129.9+20.0 and 75.0+11.2 in the male patients and 59.2%, 1.3%, 14.5%,
17.1%, 69.7%, 125.1+14.6 and 69.3+11.0 in the female patients. These indicators
were found to be significantly higher in male patients. In contrast, the rate of
V1-V4 T-wave inversion and level of D-dimer in the blood were significantly lower
in males than in females. No significant difference was observed in the remaining
observational indicators. Gender differences regarding the symptoms, signs,
disease history, lesion position and pathophysiology exist in patients with PE
and should be considered in clinical practice.