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10.1038/nature12984 http://scihub22266oqcxt.onion/10.1038/nature12984 C4514480!4514480!24429631     free     free     free       Nature 2014 ; 505 (7483): 327-34 Nephropedia Template TP {{tp|p=24429631|t=2014. The bone marrow niche for haematopoietic stem cells |pdf=|usr=}}{{24429631}} gab.com Text The bone marrow niche for haematopoietic stem cells JO: Nature http://www.kidney.de/pget.php?&tw=1&pmid=24429631 #FOAvip Niches are local tissue microenvironments that maintain and regulate stem cells. Haematopoiesis provides a paradigm for understanding mammalian stem cells and their niches, yet the haematopoietic stem cell (HSC) niche remains incompletely defined and beset by competing models. Here we review progress in elucidating the location and cellular components of the HSC niche in the bone marrow. The niche is perivascular, created partly by mesenchymal stromal cells and endothelial cells and often, but not always, located near trabecular bone. Outstanding questions concern the cellular complexity of the niche, the role of the endosteum, and functional heterogeneity among perivascular microenvironments. Twit Text FOAVip The bone marrow niche for haematopoietic stem cells ????Nature http://www.kidney.de/pget.php?&tw=1&pmid=24429631 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24429631 #FOAvip English Wikipedia <ref>{{Cite pmid|24429631}}</ref> The bone marrow niche for haematopoietic stem cells #MMPMID24429631 Morrison SJ; Scadden DT Nature 2014[Jan]; 505 (7483): 327-34 PMID24429631show ga Niches are local tissue microenvironments that maintain and regulate stem cells. Haematopoiesis provides a paradigm for understanding mammalian stem cells and their niches, yet the haematopoietic stem cell (HSC) niche remains incompletely defined and beset by competing models. Here we review progress in elucidating the location and cellular components of the HSC niche in the bone marrow. The niche is perivascular, created partly by mesenchymal stromal cells and endothelial cells and often, but not always, located near trabecular bone. Outstanding questions concern the cellular complexity of the niche, the role of the endosteum, and functional heterogeneity among perivascular microenvironments. äThe bone marrow niche for haematopoietic stem cells (epmc).pdf DeepDyve Pubget Overpricing