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2015 ; 36
(3
): 97-100
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Original technique for preoperative preparation of patients and intraoperative
localization of parathyroid adenomas
#MMPMID26188752
Pasta V
; Monteleone F
; Del Vecchio L
; Iacobelli S
; Urciuoli P
; D'Orazi V
G Chir
2015[May]; 36
(3
): 97-100
PMID26188752
show ga
Surgical approach of single parathyroid adenoma treatment is turning to a less
invasive surgery, allowing us to obtain better aesthetic results, reduction of
duration of surgical operation, reduction of post-operative morbidity and
hospital stay. Tc99m-sestaMIBI scintigraphy is mainly performed for preoperative
localization of parathyroid adenomas. Our technique is instead based on the
possibility to inhibit the interference of Tc99m-sestaMIBI uptake of the thyroid
gland by means of the administration of Lugol's solution. Indeed, to confirm the
identification and removal of the hyperfunctional parathyroid, it is accepted as
adequate an ex vivo radioactivity count of the adenoma 20% or 40% greater than
the value of the post-excisional background radioactivity, in association or not
with intraoperative measurement of PTH. This method allows us to perform surgery
with no timetable restriction, and to clearly distinguish the radioactivity of
parathyroid adenoma from that of the surrounding tissues and thyroid gland.