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10.4103/0971-5916.159250 http://scihub22266oqcxt.onion/10.4103/0971-5916.159250 C4510718!4510718!26112839     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26112839&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Indian+J+Med+Res 2015 ; 141 (4): 389-97 Nephropedia Template TP {{tp|p=26112839|t=2015. Survivin: A molecular biomarker in cancer |pdf=|usr=}}{{26112839}} gab.com Text Survivin: A molecular biomarker in cancer JO: Indian J Med Res http://www.kidney.de/pget.php?&tw=1&pmid=26112839 #FOAvip Survivin, a member of the inhibitor of apoptosis (IAP) protein family that inhibits caspases and blocks cell death, is highly expressed in most cancers and is associated with a poor clinical outcome. Survivin has consistently been identified by molecular profiling analysis to be associated with high tumour grade cancers, different disease survival and recurrence. Polymorphisms in the survivin gene are emerging as powerful tools to study the biology of the disease and have the potential to be used in disease prognosis and diagnosis. The survivin gene polymorphisms have also been reported to influence tumour aggressiveness as well as survival of cancer patients. The differential expression of survivin in cancer cells compared to normal tissues and its role as a nodal protein in a number of cellular pathways make it a high target for different therapeutics. This review discusses the complex circuitry of survivin in human cancers and gene variants of survivin, and highlights novel therapy that targets this important protein. Twit Text FOAVip Survivin: A molecular biomarker in cancer ????Indian J Med Res http://www.kidney.de/pget.php?&tw=1&pmid=26112839 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26112839 #FOAvip English Wikipedia <ref>{{Cite pmid|26112839}}</ref> Survivin: A molecular biomarker in cancer #MMPMID26112839 Jaiswal PK; Goel A; Mittal R Indian J Med Res 2015[Apr]; 141 (4): 389-97 PMID26112839show ga Survivin, a member of the inhibitor of apoptosis (IAP) protein family that inhibits caspases and blocks cell death, is highly expressed in most cancers and is associated with a poor clinical outcome. Survivin has consistently been identified by molecular profiling analysis to be associated with high tumour grade cancers, different disease survival and recurrence. Polymorphisms in the survivin gene are emerging as powerful tools to study the biology of the disease and have the potential to be used in disease prognosis and diagnosis. The survivin gene polymorphisms have also been reported to influence tumour aggressiveness as well as survival of cancer patients. The differential expression of survivin in cancer cells compared to normal tissues and its role as a nodal protein in a number of cellular pathways make it a high target for different therapeutics. This review discusses the complex circuitry of survivin in human cancers and gene variants of survivin, and highlights novel therapy that targets this important protein. äSurvivin: A molecular biomarker in cancer (epmc).pdf DeepDyve Pubget Overpricing