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Hepato-Nephrocitic System: A Novel Model of Biomarkers for Analysis of the
Ecology of Stress in Environmental Biomonitoring
#MMPMID26197058
Abdalla FC
; Domingues CE
PLoS One
2015[]; 10
(7
): e0132349
PMID26197058
show ga
Bombus presents a serious global decline of populations and even loss of species.
This phenomenon is complex and multifactorial: environmental degradation due to
increasing cultivation and grazing areas, indiscriminate use of agrochemicals,
and a plethora of xenobiotics daily discharged in the environment. We proposed
that bees have an integrated cell system, which ensures protection against
chemical stressors up to a certain limit. Therefore, this hypothesis was tested,
exposing workers of Bombus morio to cadmium, a harmful trace metal nowadays
widespread in our society. The workers were kept in BOD (26°C, RH 70%, in the
dark), fed ad libitum, and divided into a control group (n = 20) and an
experimental group (n = 20). For the first group, we offered 2 mL of distilled
water; for the experimental groups, 2 mL of cadmium at 1 ppb. In relation to the
control group, exposed bees showed that their fat body and hemocytes responded in
synchronization with pericardial cells in a topographical and temporal cascade of
events, where the fat body is the first barrier against xenobiotics, followed by
pericardial cells. The immune cells participate throughout the process. To this
system, we proposed the name of hepato-nephrocitic system (HNS), which may
explain many phenomena that remain unclear in similar research with Apis
mellifera and other species of bees, as shown in this paper. The bee's HNS is a
system of highly responsive cells to toxicants, considered a novel parameter for
the study of the ecology of stress applied in environmental management.
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