Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1186/s13287-015-0102-5 http://scihub22266oqcxt.onion/10.1186/s13287-015-0102-5 C4509778!4509778!26021558     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Stem+Cell+Res+Ther 2015 ; 6 (1): ä Nephropedia Template TP {{tp|p=26021558|t=2015. Timing for intracoronary administration of bone marrow mononuclear cells after acute ST-elevation myocardial infarction: a pilot study |pdf=|usr=}}{{26021558}} gab.com Text Timing for intracoronary administration of bone marrow mononuclear cells after acute ST-elevation myocardial infarction: a pilot study JO: Stem Cell Res Ther http://www.kidney.de/pget.php?&tw=1&pmid=26021558 #FOAvip Introduction: Most studies on intracoronary bone marrow mononuclear cell transplantation for acute myocardial infarction involve treatment 3?7 days after primary percutaneous coronary intervention (PCI); however, the optimal timing is unknown. The present study assessed the therapeutic effect at different times after ST-elevation myocardial infarction. Methods: The present trial was not blinded. A total of 104 patients with a first ST-elevation myocardial infarction and a left ventricular ejection fraction below 50 %, who had PCI of the infarct-related artery, were randomly assigned to receive intracoronary infusion of bone marrow mononuclear cells within 24 hours (group A, n = 27), 3 to 7 days after PCI (group B, n = 26), or 7 to 30 days after PCI (group C, n = 26), or to the control group (n = 25), which received saline infusion performed immediately after emergency PCI. All patients in groups A, B and C received an injection of 15 ml cell suspension containing approximately 4.9 × 108 bone marrow mononuclear cells into the infarct-related artery after successful PCI. Results: Compared to control and group C patients, group A and B patients had a significantly higher absolute increase in left ventricular ejection fraction from baseline to 12 months (change: 3.4 ± 5.7 % in control, 7.9 ± 4.9 % in group A, 6.9 ± 3.9 % in group B, 4.7 ± 3.7 % in group C), a greater decrease in left ventricular end-systolic volumes (change: ?6.4 ± 15.9 ml in control, ?20.5 ± 13.3 ml in group A, ?19.6 ± 11.1 ml in group B, ?9.4 ± 16.3 ml in group C), and significantly greater myocardial perfusion (change from baseline: ?4.7 ± 5.7 % in control, ?7.8 ± 4.5 % in group A, ?7.5 ± 2.9 % in group B, ?5.0 ± 4.0 % in group C). Group A and B patients had similar beneficial effects on cardiac function (p = 0.163) and left ventricular geometry (left ventricular end-distolic volume: p = 0.685; left ventricular end-systolic volume: p = 0.622) assessed by echocardiography, whereas group C showed similar results to those of the control group. Group B showed more expensive care (p < 0.001) and longer hospital stays during the first month after emergency PCI (p < 0.001) than group A, with a similar improvement after repeat cardiac catheterization following emergency PCI. Conclusion: Cell therapy in acute myocardial infarction patients that is given within 24 hours is similar to 3?7 days after the primary PCI. Trial registration: NCT02425358, registered 30 April 2015 Twit Text FOAVip Timing for intracoronary administration of bone marrow mononuclear cells after acute ST-elevation myocardial infarction: a pilot study ????Stem Cell Res Ther http://www.kidney.de/pget.php?&tw=1&pmid=26021558 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26021558 #FOAvip English Wikipedia <ref>{{Cite pmid|26021558}}</ref> Timing for intracoronary administration of bone marrow mononuclear cells after acute ST-elevation myocardial infarction: a pilot study #MMPMID26021558 Huang R; Yao K; Sun A; Qian J; Ge L; Zhang Y; Niu Y; Wang K; Zou Y; Ge J Stem Cell Res Ther 2015[]; 6 (1): ä PMID26021558show ga Introduction: Most studies on intracoronary bone marrow mononuclear cell transplantation for acute myocardial infarction involve treatment 3?7 days after primary percutaneous coronary intervention (PCI); however, the optimal timing is unknown. The present study assessed the therapeutic effect at different times after ST-elevation myocardial infarction. Methods: The present trial was not blinded. A total of 104 patients with a first ST-elevation myocardial infarction and a left ventricular ejection fraction below 50 %, who had PCI of the infarct-related artery, were randomly assigned to receive intracoronary infusion of bone marrow mononuclear cells within 24 hours (group A, n = 27), 3 to 7 days after PCI (group B, n = 26), or 7 to 30 days after PCI (group C, n = 26), or to the control group (n = 25), which received saline infusion performed immediately after emergency PCI. All patients in groups A, B and C received an injection of 15 ml cell suspension containing approximately 4.9 × 108 bone marrow mononuclear cells into the infarct-related artery after successful PCI. Results: Compared to control and group C patients, group A and B patients had a significantly higher absolute increase in left ventricular ejection fraction from baseline to 12 months (change: 3.4 ± 5.7 % in control, 7.9 ± 4.9 % in group A, 6.9 ± 3.9 % in group B, 4.7 ± 3.7 % in group C), a greater decrease in left ventricular end-systolic volumes (change: ?6.4 ± 15.9 ml in control, ?20.5 ± 13.3 ml in group A, ?19.6 ± 11.1 ml in group B, ?9.4 ± 16.3 ml in group C), and significantly greater myocardial perfusion (change from baseline: ?4.7 ± 5.7 % in control, ?7.8 ± 4.5 % in group A, ?7.5 ± 2.9 % in group B, ?5.0 ± 4.0 % in group C). Group A and B patients had similar beneficial effects on cardiac function (p = 0.163) and left ventricular geometry (left ventricular end-distolic volume: p = 0.685; left ventricular end-systolic volume: p = 0.622) assessed by echocardiography, whereas group C showed similar results to those of the control group. Group B showed more expensive care (p < 0.001) and longer hospital stays during the first month after emergency PCI (p < 0.001) than group A, with a similar improvement after repeat cardiac catheterization following emergency PCI. Conclusion: Cell therapy in acute myocardial infarction patients that is given within 24 hours is similar to 3?7 days after the primary PCI. Trial registration: NCT02425358, registered 30 April 2015 äTiming for intracoronary administration of bone marrow mononuclear cel(epmc).pdf DeepDyve Pubget Overpricing