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10.3892/ol.2015.3361 http://scihub22266oqcxt.onion/10.3892/ol.2015.3361 C4509079!4509079!26622537     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26622537&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncol+Lett 2015 ; 10 (2): 583-8 Nephropedia Template TP {{tp|p=26622537|t=2015. BMI-1, a promising therapeutic target for human cancer |pdf=|usr=}}{{26622537}} gab.com Text BMI-1, a promising therapeutic target for human cancer JO: Oncol Lett http://www.kidney.de/pget.php?&tw=1&pmid=26622537 #FOAvip BMI-1 oncogene is a member of the polycomb-group gene family and a transcriptional repressor. Overexpression of BMI-1 has been identified in various human cancer tissues and is known to be involved in cancer cell proliferation, cell invasion, distant metastasis, chemosensitivity and patient survival. Accumulating evidence has revealed that BMI-1 is also involved in the regulation of self-renewal, differentiation and tumor initiation of cancer stem cells (CSCs). However, the molecular mechanisms underlying these biological processes remain unclear. The present review summarized the function of BMI-1 in different human cancer types and CSCs, and discussed the signaling pathways in which BMI-1 is potentially involved. In conclusion, BMI-1 may represent a promising target for the prevention and therapy of various cancer types. Twit Text FOAVip BMI-1, a promising therapeutic target for human cancer ????Oncol Lett http://www.kidney.de/pget.php?&tw=1&pmid=26622537 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26622537 #FOAvip English Wikipedia <ref>{{Cite pmid|26622537}}</ref> BMI-1, a promising therapeutic target for human cancer #MMPMID26622537 WANG MC; LI CL; CUI J; JIAO M; WU T; JING L; NAN KJ Oncol Lett 2015[Aug]; 10 (2): 583-8 PMID26622537show ga BMI-1 oncogene is a member of the polycomb-group gene family and a transcriptional repressor. Overexpression of BMI-1 has been identified in various human cancer tissues and is known to be involved in cancer cell proliferation, cell invasion, distant metastasis, chemosensitivity and patient survival. Accumulating evidence has revealed that BMI-1 is also involved in the regulation of self-renewal, differentiation and tumor initiation of cancer stem cells (CSCs). However, the molecular mechanisms underlying these biological processes remain unclear. The present review summarized the function of BMI-1 in different human cancer types and CSCs, and discussed the signaling pathways in which BMI-1 is potentially involved. In conclusion, BMI-1 may represent a promising target for the prevention and therapy of various cancer types. äBMI-1, a promising therapeutic target for human cancer (epmc).pdf DeepDyve Pubget Overpricing