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2014 ; 54
(1
): 54-62
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gab.com Text
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Endovascular embolization of cerebral arteriovenous malformations: results of the
Japanese Registry of Neuroendovascular Therapy (JR-NET) 1 and 2
#MMPMID24292606
Kondo R
; Matsumoto Y
; Endo H
; Miyachi S
; Ezura M
; Sakai N
Neurol Med Chir (Tokyo)
2014[]; 54
(1
): 54-62
PMID24292606
show ga
This retrospective study constitutes a part of the Japanese Registry of
Neuroendovascular Therapy (JR-NET) 1 and 2. Its purpose is to evaluate the
feasibility, safety, and outcome of endovascular embolization for cerebral
arteriovenous malformations (AVMs) in Japan. Nine hundred and eighty-seven
embolization procedures were registered with JR-NET 1 and 2 (424 procedures in
122 institutions with JRNET 1 and 563 procedures in 150 institutions with JRNET
2). In total, 790 patients (80.1%) had favourable clinical outcomes defined as
modified Rankin Scale (mRS) scores 0-2 at 30 days after embolization. Complete
AVM obliteration by embolization alone was achieved in 90 procedures (9.1%). The
procedural morbidity and mortality rate was 2.5% and 0.3% per procedure,
respectively. In the multivariate logistic regression models, deep venous
drainage and embolization of four or more feeding pedicles per session were
significantly associated with any treatment-related complications (P = 0.02 and P
= 0.003, respectively). About 6 cm or more in maximum nidus diameter had a
negative correlation with complications (P = 0.003). Our study shows that
embolization of cerebral AVMs was performed with a high degree of safety and a
low rate of symptomatic complications in Japan.
|Adolescent
[MESH]
|Adult
[MESH]
|Aged
[MESH]
|Aged, 80 and over
[MESH]
|Biomarkers
[MESH]
|Cerebral Hemorrhage/etiology
[MESH]
|Child
[MESH]
|Child, Preschool
[MESH]
|Dimethyl Sulfoxide/therapeutic use
[MESH]
|Embolization, Therapeutic/adverse effects/methods/*statistics & numerical data
[MESH]
|Endovascular Procedures/statistics & numerical data
[MESH]