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10.1016/j.jaci.2009.11.001 http://scihub22266oqcxt.onion/10.1016/j.jaci.2009.11.001 C4508191!4508191!20004774     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=20004774&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       J+Allergy+Clin+Immunol 2009 ; 124 (6): 1129-40 Nephropedia Template TP {{tp|p=20004774|t=2009. Therapy of autoinflammatory syndromes |pdf=|usr=}}{{20004774}} gab.com Text Therapy of autoinflammatory syndromes JO: J Allergy Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=20004774 #FOAvip The therapy of autoinflammatory syndromes is an excellent example of the power of translational research. Recent advances in our understanding of the molecular and immunologic basis of this newly identified classification of disease have allowed for the application of novel, effective, targeted treatments with life-changing effects on patients. Although colchicine and TNF-? inhibitors are important therapies for specific autoinflammatory syndromes, the novel IL-1?targeted drugs are particularly effective for many of these diseases. Recently, the pharmaceutical industry has adopted a strategy of confirming the efficacy of new targeted drugs in often-ignored patients with orphan diseases, and US Food and Drug Administration policies have allowed for accelerated approval of these drugs, creating a win-win situation for patients and industry. This article reviews the general approach to the therapy of autoinflammatory diseases, focusing on current approved therapies and novel approaches that might be used in the future. Twit Text FOAVip Therapy of autoinflammatory syndromes ????J Allergy Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=20004774 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=20004774 #FOAvip English Wikipedia <ref>{{Cite pmid|20004774}}</ref> Therapy of autoinflammatory syndromes #MMPMID20004774 Hoffman HM J Allergy Clin Immunol 2009[Dec]; 124 (6): 1129-40 PMID20004774show ga The therapy of autoinflammatory syndromes is an excellent example of the power of translational research. Recent advances in our understanding of the molecular and immunologic basis of this newly identified classification of disease have allowed for the application of novel, effective, targeted treatments with life-changing effects on patients. Although colchicine and TNF-? inhibitors are important therapies for specific autoinflammatory syndromes, the novel IL-1?targeted drugs are particularly effective for many of these diseases. Recently, the pharmaceutical industry has adopted a strategy of confirming the efficacy of new targeted drugs in often-ignored patients with orphan diseases, and US Food and Drug Administration policies have allowed for accelerated approval of these drugs, creating a win-win situation for patients and industry. This article reviews the general approach to the therapy of autoinflammatory diseases, focusing on current approved therapies and novel approaches that might be used in the future. äTherapy of autoinflammatory syndromes (epmc).pdf DeepDyve Pubget Overpricing