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10.1097/MPH.0b013e3182830c25

http://scihub22266oqcxt.onion/10.1097/MPH.0b013e3182830c25
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C4508016!4508016 !23459377
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suck abstract from ncbi

pmid23459377
      J+Pediatr+Hematol+Oncol 2013 ; 35 (5 ): e226-8
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  • Severe thrombocytopenia in a child secondary to passive platelet antibody transfer from a plasma transfusion #MMPMID23459377
  • Collins CL ; Scott JP ; Panepinto JA ; Punzalan RC
  • J Pediatr Hematol Oncol 2013[Jul]; 35 (5 ): e226-8 PMID23459377 show ga
  • Although rare, passive transfer of platelet antibodies through blood products can result in thrombocytopenia, acute transfusion reactions, and death. We report a case of severe alloimmune thrombocytopenia from a plasma transfusion. A postliver transplant patient with a normal platelet count received fresh frozen plasma before liver biopsy. Postbiopsy, she developed cardiorespiratory distress, petechiae, and severe thrombocytopenia (platelet count 2000/?L). Her platelet count recovered to normal after 1 week. This diagnosis should be considered whenever an unexpected drop in the platelet count occurs after a plasma-rich transfusion. Conservative transfusion practices and more targeted donor screening may prevent similar events.
  • |Antigens, Human Platelet/immunology [MESH]
  • |Blood Component Transfusion/*adverse effects [MESH]
  • |Child, Preschool [MESH]
  • |Enzyme-Linked Immunosorbent Assay [MESH]
  • |Female [MESH]
  • |Humans [MESH]
  • |Isoantibodies/adverse effects/*immunology [MESH]
  • |Liver Transplantation [MESH]
  • |Plasma/*immunology [MESH]


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