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10.1089/jir.2014.0052 http://scihub22266oqcxt.onion/10.1089/jir.2014.0052 C4507134!4507134 !25756191     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25756191 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Interferon+Cytokine+Res 2015 ; 35 (7 ): 554-62 Nephropedia Template TP {{tp|p=25756191 |t=2015. Interferon Lambda Upregulates IDO1 Expression in Respiratory Epithelial Cells After Influenza Virus Infection |pdf=|usr=}}{{25756191 }} gab.com Text Interferon Lambda Upregulates IDO1 Expression in Respiratory Epithelial Cells After Influenza Virus Infection JO: J Interferon Cytokine Res http://www.kidney.de/pget.php?&tw=1&pmid=25756191 #FOAvip Influenza infection causes an increase in indoleamine 2, 3-dioxygenase (IDO) activity in the lung parenchyma. IDO catabolizes tryptophan into kynurenine, leading to immune dampening. Multiple cell types express IDO, and while IFN-? upregulates IDO in dendritic cells and macrophages, it is unclear how IDO is affected in respiratory epithelial cells during influenza infection. In this study, the role of IFN-? in IDO regulation was investigated after influenza infection of respiratory epithelial cells. IDO1 expression increased concurrently with IFN-? expression. In differentiated NHBE cells, the IDO metabolite was released basolaterally. Recombinant IFN-? upregulated IDO1 activity, and silencing of IFN-? decreased IDO1 expression during influenza infection. During IFN-? stimulation, most differentiated cell types are able to express IDO but during influenza infection, IDO is primarily expressed in uninfected cells. These studies show a role for IDO in the host response to influenza infection, and they provide insights into novel approaches for enhancing vaccine responses and therapeutic approaches. Twit Text FOAVip Interferon Lambda Upregulates IDO1 Expression in Respiratory Epithelial Cells After Influenza Virus Infection ????J Interferon Cytokine Res http://www.kidney.de/pget.php?&tw=1&pmid=25756191 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25756191 #FOAvip English Wikipedia <ref>{{Cite pmid|25756191 }}</ref> Interferon Lambda Upregulates IDO1 Expression in Respiratory Epithelial Cells After Influenza Virus Infection #MMPMID25756191 Fox JM ; Crabtree JM ; Sage LK ; Tompkins SM ; Tripp RA J Interferon Cytokine Res 2015[Jul]; 35 (7 ): 554-62 PMID25756191 show ga Influenza infection causes an increase in indoleamine 2, 3-dioxygenase (IDO) activity in the lung parenchyma. IDO catabolizes tryptophan into kynurenine, leading to immune dampening. Multiple cell types express IDO, and while IFN-? upregulates IDO in dendritic cells and macrophages, it is unclear how IDO is affected in respiratory epithelial cells during influenza infection. In this study, the role of IFN-? in IDO regulation was investigated after influenza infection of respiratory epithelial cells. IDO1 expression increased concurrently with IFN-? expression. In differentiated NHBE cells, the IDO metabolite was released basolaterally. Recombinant IFN-? upregulated IDO1 activity, and silencing of IFN-? decreased IDO1 expression during influenza infection. During IFN-? stimulation, most differentiated cell types are able to express IDO but during influenza infection, IDO is primarily expressed in uninfected cells. These studies show a role for IDO in the host response to influenza infection, and they provide insights into novel approaches for enhancing vaccine responses and therapeutic approaches. |*Up-Regulation [MESH] |Animals [MESH] |Cell Death [MESH] |Cell Line [MESH] |Cell Survival [MESH] |Cytokines/*metabolism [MESH] |Dogs [MESH] |Epithelial Cells/enzymology/*virology [MESH] |Humans [MESH] |Indoleamine-Pyrrole 2,3,-Dioxygenase/antagonists & inhibitors/*metabolism [MESH] |Influenza, Human/metabolism/virology [MESH] |Interferons [MESH] |Interleukins/*metabolism [MESH] |Lung/pathology [MESH] |Mice [MESH] |Orthomyxoviridae Infections/*metabolism/virology [MESH]Interferon Lambda Upregulates IDO1 Expression in Respiratory Epithelia(epmc).pdf DeepDyve Pubget Overpricing