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2015 ; 4
(6
): 316-9
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Pharmacometrics Markup Language (PharmML): Opening New Perspectives for Model
Exchange in Drug Development
#MMPMID26225259
Swat MJ
; Moodie S
; Wimalaratne SM
; Kristensen NR
; Lavielle M
; Mari A
; Magni P
; Smith MK
; Bizzotto R
; Pasotti L
; Mezzalana E
; Comets E
; Sarr C
; Terranova N
; Blaudez E
; Chan P
; Chard J
; Chatel K
; Chenel M
; Edwards D
; Franklin C
; Giorgino T
; Glont M
; Girard P
; Grenon P
; Harling K
; Hooker AC
; Kaye R
; Keizer R
; Kloft C
; Kok JN
; Kokash N
; Laibe C
; Laveille C
; Lestini G
; Mentré F
; Munafo A
; Nordgren R
; Nyberg HB
; Parra-Guillen ZP
; Plan E
; Ribba B
; Smith G
; Trocóniz IF
; Yvon F
; Milligan PA
; Harnisch L
; Karlsson M
; Hermjakob H
; Le Novère N
CPT Pharmacometrics Syst Pharmacol
2015[Jun]; 4
(6
): 316-9
PMID26225259
show ga
The lack of a common exchange format for mathematical models in pharmacometrics
has been a long-standing problem. Such a format has the potential to increase
productivity and analysis quality, simplify the handling of complex workflows,
ensure reproducibility of research, and facilitate the reuse of existing model
resources. Pharmacometrics Markup Language (PharmML), currently under development
by the Drug Disease Model Resources (DDMoRe) consortium, is intended to become an
exchange standard in pharmacometrics by providing means to encode models, trial
designs, and modeling steps.