Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1161/STROKEAHA.113.004137 http://scihub22266oqcxt.onion/10.1161/STROKEAHA.113.004137 C4504196!4504196!24619391     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Stroke 2014 ; 45 (4): 988-93 Nephropedia Template TP {{tp|p=24619391|t=2014. Assessing the clinical impact of residual cortical disconnection after ischemic strokes |pdf=|usr=}}{{24619391}} gab.com Text Assessing the clinical impact of residual cortical disconnection after ischemic strokes JO: Stroke http://www.kidney.de/pget.php?&tw=1&pmid=24619391 #FOAvip Background and purpose: Studies assessing the relationship between chronic post-stroke language impairment (aphasia), and ischemic brain damage usually rely on measuring the extent of brain necrosis observed on magnetic resonance image (MRI). Nonetheless, clinical observation suggests that patients can exhibit deficits that are more severe than what would be expected based on lesion location and size. This phenomenon is commonly explained as being the result of cortical disconnection. To understand if disconnection contributes to clinical symptoms, we assessed the relationship between language impairments and structural brain connectivity (the connectome) in patients with chronic aphasia after a stroke Methods: Thirty-nine patients with chronic aphasia underwent language assessment and MRI scanning. Relying on MRI data, we reconstructed the individual connectome from T1 weighted and diffusion tensor imaging (DTI). Deterministic fiber tractography was employed to assess connectivity between each possible pair of cortical Brodmann areas (BA). Multiple linear regression analyses were performed to evaluate the relationship between language performance and cortical necrosis and cortical disconnection. Results: We observed that structural disconnection of BA 45 (spared by the necrotic tissue) was independently associated with naming performance, controlling for the extent of BA 45 necrosis (F=4.62, p<0.01; necrosis: ?=0.43; p=0.03; disconnection ?=1.21; p<0.001). Conclusions: We suggest that cortical disconnection, as measured by the structural connectome, is an independent predictor of naming impairment in patients with chronic aphasia. The full extent of clinically relevant brain damage after an ischemic stroke may be underappreciated by visual inspection of cortical necrosis alone. Twit Text FOAVip Assessing the clinical impact of residual cortical disconnection after ischemic strokes ????Stroke http://www.kidney.de/pget.php?&tw=1&pmid=24619391 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24619391 #FOAvip English Wikipedia <ref>{{Cite pmid|24619391}}</ref> Assessing the clinical impact of residual cortical disconnection after ischemic strokes #MMPMID24619391 Bonilha L; Rorden C; Fridriksson J Stroke 2014[Apr]; 45 (4): 988-93 PMID24619391show ga Background and purpose: Studies assessing the relationship between chronic post-stroke language impairment (aphasia), and ischemic brain damage usually rely on measuring the extent of brain necrosis observed on magnetic resonance image (MRI). Nonetheless, clinical observation suggests that patients can exhibit deficits that are more severe than what would be expected based on lesion location and size. This phenomenon is commonly explained as being the result of cortical disconnection. To understand if disconnection contributes to clinical symptoms, we assessed the relationship between language impairments and structural brain connectivity (the connectome) in patients with chronic aphasia after a stroke Methods: Thirty-nine patients with chronic aphasia underwent language assessment and MRI scanning. Relying on MRI data, we reconstructed the individual connectome from T1 weighted and diffusion tensor imaging (DTI). Deterministic fiber tractography was employed to assess connectivity between each possible pair of cortical Brodmann areas (BA). Multiple linear regression analyses were performed to evaluate the relationship between language performance and cortical necrosis and cortical disconnection. Results: We observed that structural disconnection of BA 45 (spared by the necrotic tissue) was independently associated with naming performance, controlling for the extent of BA 45 necrosis (F=4.62, p<0.01; necrosis: ?=0.43; p=0.03; disconnection ?=1.21; p<0.001). Conclusions: We suggest that cortical disconnection, as measured by the structural connectome, is an independent predictor of naming impairment in patients with chronic aphasia. The full extent of clinically relevant brain damage after an ischemic stroke may be underappreciated by visual inspection of cortical necrosis alone. äAssessing the clinical impact of residual cortical disconnection after(epmc).pdf DeepDyve Pubget Overpricing