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10.1186/s12872-015-0066-5

http://scihub22266oqcxt.onion/10.1186/s12872-015-0066-5
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suck abstract from ncbi


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pmid26169782      BMC+Cardiovasc+Disord 2015 ; 15 (ä): ä
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  • Performance of Sokolow-Lyon index in detection of echocardiographically diagnosed left ventricular hypertrophy in a normal Eastern German population - results of the CARLA study #MMPMID26169782
  • Schröder J; Nuding S; Müller-Werdan U; Werdan K; Kluttig A; Russ M; Greiser KH; Kors JA; Haerting J; Medenwald D
  • BMC Cardiovasc Disord 2015[]; 15 (ä): ä PMID26169782show ga
  • Background: Arterial hypertension is a common disease with high prevalence in the general population. Left ventricular hypertrophy (LVH) is an independent risk factor in arterial hypertension. Electrocardiographic indices like the Sokolow-Lyon index (SLI) are recommended as diagnostic screening methods for LVH.We assessed the diagnostic performance of the SLI in a cohort of a large general population. Methods: We used electrocardiographic and echocardiographic data from the prospective, population-based cohort study CARdio-vascular Disease, Living and Ageing in Halle (CARLA). Linear and logistic regression models were used to assess the association of SLI with LVH. To assess the impact of the body-mass-index (BMI), we performed interaction analyses. Results: AUC of SLI to predict LVH was 55.3 %, sensitivity of the SLI was 5 %, specificity 97 %. We found a significant association of SLI after covariate-adjustment with echocardiographically detected LVH (increase of left-ventricular mass index, LVMI 7.0 g/m2 per 1 mV increase of SLI, p??30 kg/m2) we found the strongest association with an increase of 9.2 g/m2 per 1 mV. Conclusions: Although statistically significant, relations of SLI and echocardiographic parameters of LVH were weak and mainly driven by the increase in LVIDd, implicating a more eccentric type of LVH in the collective. The relations were strongest when obese subjects were taken into account. Our data do not favour the SLI as a diagnostic screening test to identify patients at risk for LVH, especially in non-obese subjects without eccentric LVH.
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