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10.3390/life5021019 http://scihub22266oqcxt.onion/10.3390/life5021019 C4500129!4500129!25815781     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Life+(Basel) 2015 ; 5 (2): 1019-53 Nephropedia Template TP {{tp|p=25815781|t=2015. Engineering Protocells: Prospects for Self-Assembly and Nanoscale Production-Lines |pdf=|usr=}}{{25815781}} gab.com Text Engineering Protocells: Prospects for Self-Assembly and Nanoscale Production-Lines JO: Life (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=25815781 #FOAvip The increasing ease of producing nucleic acids and proteins to specification offers potential for design and fabrication of artificial synthetic ?organisms? with a myriad of possible capabilities. The prospects for these synthetic organisms are significant, with potential applications in diverse fields including synthesis of pharmaceuticals, sources of renewable fuel and environmental cleanup. Until now, artificial cell technology has been largely restricted to the modification and metabolic engineering of living unicellular organisms. This review discusses emerging possibilities for developing synthetic protocell ?machines? assembled entirely from individual biological components. We describe a host of recent technological advances that could potentially be harnessed in design and construction of synthetic protocells, some of which have already been utilized toward these ends. More elaborate designs include options for building self-assembling machines by incorporating cellular transport and assembly machinery. We also discuss production in miniature, using microfluidic production lines. While there are still many unknowns in the design, engineering and optimization of protocells, current technologies are now tantalizingly close to the capabilities required to build the first prototype protocells with potential real-world applications. Twit Text FOAVip Engineering Protocells: Prospects for Self-Assembly and Nanoscale Production-Lines ????Life (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=25815781 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25815781 #FOAvip English Wikipedia <ref>{{Cite pmid|25815781}}</ref> Engineering Protocells: Prospects for Self-Assembly and Nanoscale Production-Lines #MMPMID25815781 Miller DM; Gulbis JM Life (Basel) 2015[Jun]; 5 (2): 1019-53 PMID25815781show ga The increasing ease of producing nucleic acids and proteins to specification offers potential for design and fabrication of artificial synthetic ?organisms? with a myriad of possible capabilities. The prospects for these synthetic organisms are significant, with potential applications in diverse fields including synthesis of pharmaceuticals, sources of renewable fuel and environmental cleanup. Until now, artificial cell technology has been largely restricted to the modification and metabolic engineering of living unicellular organisms. This review discusses emerging possibilities for developing synthetic protocell ?machines? assembled entirely from individual biological components. We describe a host of recent technological advances that could potentially be harnessed in design and construction of synthetic protocells, some of which have already been utilized toward these ends. More elaborate designs include options for building self-assembling machines by incorporating cellular transport and assembly machinery. We also discuss production in miniature, using microfluidic production lines. While there are still many unknowns in the design, engineering and optimization of protocells, current technologies are now tantalizingly close to the capabilities required to build the first prototype protocells with potential real-world applications. äEngineering Protocells: Prospects for Self-Assembly and Nanoscale Prod(epmc).pdf DeepDyve Pubget Overpricing