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2014 ; 95
(12
): 2470-83
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English Wikipedia
What do we really know about the safety of tai chi?: A systematic review of
adverse event reports in randomized trials
#MMPMID24878398
Wayne PM
; Berkowitz DL
; Litrownik DE
; Buring JE
; Yeh GY
Arch Phys Med Rehabil
2014[Dec]; 95
(12
): 2470-83
PMID24878398
show ga
OBJECTIVE: To systematically review the frequency and quality of adverse event
(AE) reports in randomized controlled trials (RCTs) of tai chi (TC). DATA
SOURCES: Electronic searches of PubMed/MEDLINE and additional databases from
inception through March 2013 of English-language RCTs. Search terms included tai
chi, taiji, and tai chi chuan. Data were independently extracted by 2
investigators. STUDY SELECTION: We included all available RCTs that were
published in English and used TC as an intervention. Inclusion and exclusion
criteria of studies were reported in accordance with the Preferred Reporting
Items for Systematic Reviews and Meta-Analyses guidelines. DATA EXTRACTION:
Eligible RCTs were categorized with respect to AE reporting: no mention of
protocol for monitoring AEs or reports of AEs, and reports of AEs either with or
without explicit protocol for monitoring AEs. DATA SYNTHESIS: There were 153
eligible RCTs identified; most targeted older adults. Only 50 eligible trials
(33%) included reporting of AEs; of these, only 18 trials (12% overall) also
reported an explicit AE monitoring protocol. Protocols varied with respect to the
rigor of systematic monitoring in both the TC and comparison groups. Reported AEs
were typically minor and expected and primarily musculoskeletal related (eg, knee
and back pain); no intervention-related serious AEs were reported. CONCLUSIONS:
TC is unlikely to result in serious AEs, but it may be associated with minor
musculoskeletal aches and pains. However, poor and inconsistent reporting of AEs
greatly limits the conclusions that can be drawn regarding the safety of TC.