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10.2147/IJN.S78308 http://scihub22266oqcxt.onion/10.2147/IJN.S78308 C4498719!4498719!26170667     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Nanomedicine 2015 ; 10 (ä): 4321-40 Nephropedia Template TP {{tp|p=26170667|t=2015. Central nervous system toxicity of metallic nanoparticles |pdf=|usr=}}{{26170667}} gab.com Text Central nervous system toxicity of metallic nanoparticles JO: Int J Nanomedicine http://www.kidney.de/pget.php?&tw=1&pmid=26170667 #FOAvip Nanomaterials (NMs) are increasingly used for the therapy, diagnosis, and monitoring of disease- or drug-induced mechanisms in the human biological system. In view of their small size, after certain modifications, NMs have the capacity to bypass or cross the blood?brain barrier. Nanotechnology is particularly advantageous in the field of neurology. Examples may include the utilization of nanoparticle (NP)-based drug carriers to readily cross the blood?brain barrier to treat central nervous system (CNS) diseases, nanoscaffolds for axonal regeneration, nanoelectromechanical systems in neurological operations, and NPs in molecular imaging and CNS imaging. However, NPs can also be potentially hazardous to the CNS in terms of nano-neurotoxicity via several possible mechanisms, such as oxidative stress, autophagy, and lysosome dysfunction, and the activation of certain signaling pathways. In this review, we discuss the dual effect of NMs on the CNS and the mechanisms involved. The limitations of the current research are also discussed. Twit Text FOAVip Central nervous system toxicity of metallic nanoparticles ????Int J Nanomedicine http://www.kidney.de/pget.php?&tw=1&pmid=26170667 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26170667 #FOAvip English Wikipedia <ref>{{Cite pmid|26170667}}</ref> Central nervous system toxicity of metallic nanoparticles #MMPMID26170667 Feng X; Chen A; Zhang Y; Wang J; Shao L; Wei L Int J Nanomedicine 2015[]; 10 (ä): 4321-40 PMID26170667show ga Nanomaterials (NMs) are increasingly used for the therapy, diagnosis, and monitoring of disease- or drug-induced mechanisms in the human biological system. In view of their small size, after certain modifications, NMs have the capacity to bypass or cross the blood?brain barrier. Nanotechnology is particularly advantageous in the field of neurology. Examples may include the utilization of nanoparticle (NP)-based drug carriers to readily cross the blood?brain barrier to treat central nervous system (CNS) diseases, nanoscaffolds for axonal regeneration, nanoelectromechanical systems in neurological operations, and NPs in molecular imaging and CNS imaging. However, NPs can also be potentially hazardous to the CNS in terms of nano-neurotoxicity via several possible mechanisms, such as oxidative stress, autophagy, and lysosome dysfunction, and the activation of certain signaling pathways. In this review, we discuss the dual effect of NMs on the CNS and the mechanisms involved. The limitations of the current research are also discussed. äCentral nervous system toxicity of metallic nanoparticles (epmc).pdf DeepDyve Pubget Overpricing