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10.1016/j.actbio.2011.01.022 http://scihub22266oqcxt.onion/10.1016/j.actbio.2011.01.022 C4497587!4497587!21255691     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Acta+Biomater 2011 ; 7 (5): 2101-8 Nephropedia Template TP {{tp|p=21255691|t=2011. Elastic fibers in the aortic valve spongiosa: a fresh perspective on its structure and role in overall tissue function |pdf=|usr=}}{{21255691}} gab.com Text Elastic fibers in the aortic valve spongiosa: a fresh perspective on its structure and role in overall tissue function JO: Acta Biomater http://www.kidney.de/pget.php?&tw=1&pmid=21255691 #FOAvip This study characterized the elastic fiber structure within the aortic valve spongiosa, the middle layer of the tri-laminate leaflet. The layer is rich in glycosaminoglycans and proteoglycans, through which it resists compression and lubricates shear between the outer layers. Elastin in this layer forms a fine, interweaving structure, yet it is unclear how this particular structure, which uses elasticity to preload the leaflet, assists spongiosa function. In this study, immunohistochemistry and scanning electron microscopy were used to characterize spongiosa elastin, as well as investigate regional differences in structure. Immunohistochemistry for elastin highlighted an intermediate structure that varied in thickness and density between regions. In particular, the spongiosa elastin was thicker in the hinge and coaptation region than in the belly. Scanning electron microscopy of NaOH-digested leaflets showed a rectilinear pattern of elastic fibers in the hinge and coaptation region, as opposed to a radially oriented stripe pattern in the belly. In conclusion, elastic fibers in the spongiosa connect the two outer layers and vary regionally in structure, while possible playing a role in responding to regionally specific loading patterns. Twit Text FOAVip Elastic fibers in the aortic valve spongiosa: a fresh perspective on its structure and role in overall tissue function ????Acta Biomater http://www.kidney.de/pget.php?&tw=1&pmid=21255691 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=21255691 #FOAvip English Wikipedia <ref>{{Cite pmid|21255691}}</ref> Elastic fibers in the aortic valve spongiosa: a fresh perspective on its structure and role in overall tissue function #MMPMID21255691 Tseng H; Grande-Allen KJ Acta Biomater 2011[May]; 7 (5): 2101-8 PMID21255691show ga This study characterized the elastic fiber structure within the aortic valve spongiosa, the middle layer of the tri-laminate leaflet. The layer is rich in glycosaminoglycans and proteoglycans, through which it resists compression and lubricates shear between the outer layers. Elastin in this layer forms a fine, interweaving structure, yet it is unclear how this particular structure, which uses elasticity to preload the leaflet, assists spongiosa function. In this study, immunohistochemistry and scanning electron microscopy were used to characterize spongiosa elastin, as well as investigate regional differences in structure. Immunohistochemistry for elastin highlighted an intermediate structure that varied in thickness and density between regions. In particular, the spongiosa elastin was thicker in the hinge and coaptation region than in the belly. Scanning electron microscopy of NaOH-digested leaflets showed a rectilinear pattern of elastic fibers in the hinge and coaptation region, as opposed to a radially oriented stripe pattern in the belly. In conclusion, elastic fibers in the spongiosa connect the two outer layers and vary regionally in structure, while possible playing a role in responding to regionally specific loading patterns. äElastic fibers in the aortic valve spongiosa: a fresh perspective on i(epmc).pdf DeepDyve Pubget Overpricing