Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

http://scihub22266oqcxt.onion/ C4496367!4496367!25865044     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncotarget 2015 ; 6 (12): 10460-72 Nephropedia Template TP {{tp|p=25865044|t=2015. Icaritin suppresses multiple myeloma, by inhibiting IL-6/JAK2/STAT3 |pdf=|usr=}}{{25865044}} gab.com Text Icaritin suppresses multiple myeloma, by inhibiting IL-6/JAK2/STAT3 JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=25865044 #FOAvip Icaritin is an active prenylflavonoid derived from Epimedium genus, a traditional Chinese medicine. Icaritin has a wide range of pharmacological and biological activities, including cardiovascular function improvement, hormone regulation and antitumor activity. Here, we investigated the effect of icaritin on multiple myeloma (MM) in vitro and in vivo. Icaritin inhibited cell growth of MM cell line and primary MM cells. In contrast, icaritin had low or no cytotoxic effect on normal hematopoiesis. We also demonstrated that in MM xenograft mouse models, icaritin suppressed tumor growth and decreased serum IL-6 and IgE levels, but did not show adverse reactions such as body weight loss. The anti-MM activity of icaritin was mainly mediated by inhibiting IL-6/JAK2/STAT3 signaling. We suggest that icaritin can be further tested in clinical trials in MM. Twit Text FOAVip Icaritin suppresses multiple myeloma, by inhibiting IL-6/JAK2/STAT3 ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=25865044 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25865044 #FOAvip English Wikipedia <ref>{{Cite pmid|25865044}}</ref> Icaritin suppresses multiple myeloma, by inhibiting IL-6/JAK2/STAT3 #MMPMID25865044 Zhu S; Wang Z; Li Z; Peng H; Luo Y; Deng M; Li R; Dai C; Xu Y; Liu S; Zhang G Oncotarget 2015[Apr]; 6 (12): 10460-72 PMID25865044show ga Icaritin is an active prenylflavonoid derived from Epimedium genus, a traditional Chinese medicine. Icaritin has a wide range of pharmacological and biological activities, including cardiovascular function improvement, hormone regulation and antitumor activity. Here, we investigated the effect of icaritin on multiple myeloma (MM) in vitro and in vivo. Icaritin inhibited cell growth of MM cell line and primary MM cells. In contrast, icaritin had low or no cytotoxic effect on normal hematopoiesis. We also demonstrated that in MM xenograft mouse models, icaritin suppressed tumor growth and decreased serum IL-6 and IgE levels, but did not show adverse reactions such as body weight loss. The anti-MM activity of icaritin was mainly mediated by inhibiting IL-6/JAK2/STAT3 signaling. We suggest that icaritin can be further tested in clinical trials in MM. äIcaritin suppresses multiple myeloma, by inhibiting IL-6/JAK2/STAT3 (epmc).pdf DeepDyve Pubget Overpricing