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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Gastroenterol+Hepatol+Bed+Bench
2015 ; 8
(Suppl 1
): S15-22
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gab.com Text
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English Wikipedia
Genetic and molecular aspects of Helicobacter pylori in gastritis, pre- cancerous
conditions and gastric adenocrcinoma
#MMPMID26171133
Shadifar M
; Ataee R
; Ataie A
; Heydari Gorgi AM
; Nasri Nasrabadi N
; Nouri S
Gastroenterol Hepatol Bed Bench
2015[Spr]; 8
(Suppl 1
): S15-22
PMID26171133
show ga
Gastric adenocarcinoma is one of the most common malignancies worldwide. Many
ethological causes have been introduced among which helicobacter pylori, as a
gram-negative bacterium has been considered as an important pathological
facilitating factor. This agent is also associated with different digestive
diseases, such as gastritis, peptic ulcer, and mucosa-associated lymphoid tissue
lymphoma. Recently, scientists have been described some molecular aspects that
show the role of some apoptotic genes and proteins; for example: P53, Bcl2, C-Myc
and Rb-suppressor systems in the H. pylori pathogenesis. Also the relationship
between nitric oxide (NOSi genotype) with H. pylori infection has been shown. The
aim of this mini-review is to explain better these genetically aspects of
H.pylori pathogenesis.