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10.1101/gad.264234.115 http://scihub22266oqcxt.onion/10.1101/gad.264234.115 C4495399!4495399!26109051     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Genes+Dev 2015 ; 29 (12): 1285-97 Nephropedia Template TP {{tp|p=26109051|t=2015. Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP |pdf=|usr=}}{{26109051}} gab.com Text Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP JO: Genes Dev http://www.kidney.de/pget.php?&tw=1&pmid=26109051 #FOAvip In this study, Chen et al. investigate the physiological importance of YAP phosphorylation in regulating endogenous YAP activity. Using mutant YapS112A knock-in mice, they found that the mice show a compensatory decrease in YAP protein levels due to increased phosphorylation at a mammalian-specific phosphodegron site on YAP. The results provide novel insight into a homeostatic mechanism that maintains physiological levels of YAP activity, which could work to prevent oncogenic activation of YAP. Twit Text FOAVip Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP ????Genes Dev http://www.kidney.de/pget.php?&tw=1&pmid=26109051 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26109051 #FOAvip English Wikipedia <ref>{{Cite pmid|26109051}}</ref> Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP #MMPMID26109051 Chen Q; Zhang N; Xie R; Wang W; Cai J; Choi KS; David KK; Huang B; Yabuta N; Nojima H; Anders RA; Pan D Genes Dev 2015[Jun]; 29 (12): 1285-97 PMID26109051show ga In this study, Chen et al. investigate the physiological importance of YAP phosphorylation in regulating endogenous YAP activity. Using mutant YapS112A knock-in mice, they found that the mice show a compensatory decrease in YAP protein levels due to increased phosphorylation at a mammalian-specific phosphodegron site on YAP. The results provide novel insight into a homeostatic mechanism that maintains physiological levels of YAP activity, which could work to prevent oncogenic activation of YAP. äHomeostatic control of Hippo signaling activity revealed by an endogen(epmc).pdf DeepDyve Pubget Overpricing