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http://scihub22266oqcxt.onion/ C4494962!4494962!25788275     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncotarget 2015 ; 6 (14): 12625-36 Nephropedia Template TP {{tp|p=25788275|t=2015. MAP17 (PDZKIP1) as a novel prognostic biomarker for laryngeal cancer |pdf=|usr=}}{{25788275}} gab.com Text MAP17 (PDZKIP1) as a novel prognostic biomarker for laryngeal cancer JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=25788275 #FOAvip Larynx cancer organ preservation treatments with chemo and radiotherapy have substantially improved laryngoesophageal dysfunction-free survival. However, both of them lead to a high incidence of acute and chronic toxicities and a significant number of patients relapse. To date, there is no evidence available to establish the group of patients that may benefit from preservation approaches and clinical criteria such as primary tumor extension or pretreatment tracheotomy are not validated. MAP17 is a small non-glycosylated membrane protein overexpressed in carcinomas. The tumoral behavior induced by MAP17 is associated with reactive oxygen species production in which SGLT1 seems involved. In this study we found that the levels of MAP17 were related to clinical findings and survival in a cohort of 58 patients with larynx cancer. MAP17 expression is associated with overall survival (p<0.001) and laryngoesophageal dysfunction-free survival (p=0.002). Locoregional control in patients with high MAP17 showed better outcomes than those with low MAP17 (p=0.016). Besides, a positive correlation was observed between MAP17 expression and SGLT (p=0.022) and the combination of high levels of MAP17/SGLT also led to an increased overall survival (p=0,028). These findings suggest that MAP17, alone or in combination with SGLT1, may become a novel predictive biomarker for laryngeal carcinoma. Twit Text FOAVip MAP17 (PDZKIP1) as a novel prognostic biomarker for laryngeal cancer ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=25788275 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25788275 #FOAvip English Wikipedia <ref>{{Cite pmid|25788275}}</ref> MAP17 (PDZKIP1) as a novel prognostic biomarker for laryngeal cancer #MMPMID25788275 de Miguel-Luken MJ; Chaves-Conde M; de Miguel-Luken V; Muñoz-Galván S; López-Guerra JL; Mateos JC; Pachón J; Chinchón D; Suarez V; Carnero A Oncotarget 2015[May]; 6 (14): 12625-36 PMID25788275show ga Larynx cancer organ preservation treatments with chemo and radiotherapy have substantially improved laryngoesophageal dysfunction-free survival. However, both of them lead to a high incidence of acute and chronic toxicities and a significant number of patients relapse. To date, there is no evidence available to establish the group of patients that may benefit from preservation approaches and clinical criteria such as primary tumor extension or pretreatment tracheotomy are not validated. MAP17 is a small non-glycosylated membrane protein overexpressed in carcinomas. The tumoral behavior induced by MAP17 is associated with reactive oxygen species production in which SGLT1 seems involved. In this study we found that the levels of MAP17 were related to clinical findings and survival in a cohort of 58 patients with larynx cancer. MAP17 expression is associated with overall survival (p<0.001) and laryngoesophageal dysfunction-free survival (p=0.002). Locoregional control in patients with high MAP17 showed better outcomes than those with low MAP17 (p=0.016). Besides, a positive correlation was observed between MAP17 expression and SGLT (p=0.022) and the combination of high levels of MAP17/SGLT also led to an increased overall survival (p=0,028). These findings suggest that MAP17, alone or in combination with SGLT1, may become a novel predictive biomarker for laryngeal carcinoma. äMAP17 (PDZKIP1) as a novel prognostic biomarker for laryngeal cancer (epmc).pdf DeepDyve Pubget Overpricing