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10.3390/cells4020218

http://scihub22266oqcxt.onion/10.3390/cells4020218
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C4493457!4493457!26024215
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suck abstract from ncbi


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pmid26024215      Cells 2015 ; 4 (2): 218-33
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  • Recent Advances in Elucidating the Genetic Mechanisms of Nephrogenesis Using Zebrafish #MMPMID26024215
  • Cheng CN; Verdun VA; Wingert RA
  • Cells 2015[Jun]; 4 (2): 218-33 PMID26024215show ga
  • The kidney is comprised of working units known as nephrons, which are epithelial tubules that contain a series of specialized cell types organized into a precise pattern of functionally distinct segment domains. There is a limited understanding of the genetic mechanisms that establish these discrete nephron cell types during renal development. The zebrafish embryonic kidney serves as a simplified yet conserved vertebrate model to delineate how nephron segments are patterned from renal progenitors. Here, we provide a concise review of recent advances in this emerging field, and discuss how continued research using zebrafish genetics can be applied to gain insightsabout nephrogenesis.
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