Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.3390/cancers7020538 http://scihub22266oqcxt.onion/10.3390/cancers7020538 C4491669!4491669!25815458     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cancers+(Basel) 2015 ; 7 (2): 538-55 Nephropedia Template TP {{tp|p=25815458|t=2015. Glioblastoma: Molecular Pathways, Stem Cells and Therapeutic Targets |pdf=|usr=}}{{25815458}} gab.com Text Glioblastoma: Molecular Pathways, Stem Cells and Therapeutic Targets JO: Cancers (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=25815458 #FOAvip Glioblastoma (GBM), a WHO-defined Grade IV astrocytoma, is the most common and aggressive CNS malignancy. Despite current treatment modalities, the survival time remains dismal. The main cause of mortality in patients with this disease is reoccurrence of the malignancy, which is attributed to treatment-resistant cancer stem cells within and surrounding the primary tumor. Inclusion of novel therapies, such as immuno- and DNA-based therapy, may provide better means of treating GBM. Furthermore, manipulation of recently discovered non-coding microRNAs, some of which regulate tumor growth through the development and maintenance of GBM stem cells, could provide new prospective therapies. Studies conducted by The Cancer Genome Atlas (TCGA) also demonstrate the role of molecular pathways, specifically the activated PI3K/AKT/mTOR pathway, in GBM tumorigenesis. Inhibition of the aforementioned pathway may provide a more direct and targeted method to GBM treatment. The combination of these treatment modalities may provide an innovative therapeutic approach for the management of GBM. Twit Text FOAVip Glioblastoma: Molecular Pathways, Stem Cells and Therapeutic Targets ????Cancers (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=25815458 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25815458 #FOAvip English Wikipedia <ref>{{Cite pmid|25815458}}</ref> Glioblastoma: Molecular Pathways, Stem Cells and Therapeutic Targets #MMPMID25815458 Jhanwar-Uniyal M; Labagnara M; Friedman M; Kwasnicki A; Murali R Cancers (Basel) 2015[Jun]; 7 (2): 538-55 PMID25815458show ga Glioblastoma (GBM), a WHO-defined Grade IV astrocytoma, is the most common and aggressive CNS malignancy. Despite current treatment modalities, the survival time remains dismal. The main cause of mortality in patients with this disease is reoccurrence of the malignancy, which is attributed to treatment-resistant cancer stem cells within and surrounding the primary tumor. Inclusion of novel therapies, such as immuno- and DNA-based therapy, may provide better means of treating GBM. Furthermore, manipulation of recently discovered non-coding microRNAs, some of which regulate tumor growth through the development and maintenance of GBM stem cells, could provide new prospective therapies. Studies conducted by The Cancer Genome Atlas (TCGA) also demonstrate the role of molecular pathways, specifically the activated PI3K/AKT/mTOR pathway, in GBM tumorigenesis. Inhibition of the aforementioned pathway may provide a more direct and targeted method to GBM treatment. The combination of these treatment modalities may provide an innovative therapeutic approach for the management of GBM. äGlioblastoma: Molecular Pathways, Stem Cells and Therapeutic Targets (epmc).pdf DeepDyve Pubget Overpricing