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2015 ; 2015
(ä): 478789
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Pulmonary Mucormycosis in a Patient with Systemic Lupus Erythematosus: A
Diagnostic and Treatment Challenge
#MMPMID26185693
Hung HC
; Shen GY
; Chen SC
; Yeo KJ
; Tsao SM
; Lee MC
; Lee YT
Case Rep Infect Dis
2015[]; 2015
(ä): 478789
PMID26185693
show ga
Pulmonary mucormycosis is commonly encountered in patients with diabetic
ketoacidosis, hematologic malignancies, neutropenia, organ or hematopoietic stem
cell transplantation, and malignancy, but it rarely occurs in high-risk patients
with systemic lupus erythematosus (SLE). We present the case of a 40-year-old SLE
female with fulminant pneumonia after remission of nephritis treated with
rituximab, who developed severe pulmonary mucormycosis that led to her rapid
death from acute respiratory failure and acute respiratory distress syndrome.
Pulmonary mucormycosis has a high mortality rate. However, with early diagnosis
and antifungal therapy with lipid formulation-liposomal amphotericin B and
surgical removal of the infected area, the outcome can be improved.