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10.1007/s13238-015-0177-x

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C4491053!4491053!26081469
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suck abstract from ncbi


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pmid26081469      Protein+Cell 2015 ; 6 (7): 472-5
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  • Eliminate mitochondrial diseases by gene editing in germ-line cells and embryos #MMPMID26081469
  • Wang S; Yi F; Qu J
  • Protein Cell 2015[Jul]; 6 (7): 472-5 PMID26081469show ga
  • Nuclease-based gene editing technologies have opened up opportunities for correcting human genetic diseases. For the first time, scientists achieved targeted gene editing of mitochondrial DNA in mouse oocytes fused with patient cells. This fascinating progression may encourage the development of novel therapy for human maternally inherent mitochondrial diseases.
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