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10.3390/ijms160612958 http://scihub22266oqcxt.onion/10.3390/ijms160612958 C4490481!4490481!26062132     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Mol+Sci 2015 ; 16 (6): 12958-85 Nephropedia Template TP {{tp|p=26062132|t=2015. Chemokine-Derived Peptides: Novel Antimicrobial and Antineoplasic Agents |pdf=|usr=}}{{26062132}} gab.com Text Chemokine-Derived Peptides: Novel Antimicrobial and Antineoplasic Agents JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=26062132 #FOAvip Chemokines are a burgeoning family of chemotactic cytokines displaying a broad array of functions such as regulation of homeostatic leukocyte traffic and development, as well as activating the innate immune system. Their role in controlling early and late inflammatory stages is now well recognized. An improper balance either in chemokine synthesis or chemokine receptor expression contributes to various pathological disorders making chemokines and their receptors a useful therapeutic target. Research in this area is progressing rapidly, and development of novel agents based on chemokine/chemokine receptors antagonist functions are emerging as attractive alternative drugs. Some of these novel agents include generation of chemokine-derived peptides (CDP) with potential agonist and antagonist effects on inflammation, cancer and against bacterial infections. CDP have been generated mainly from N- and C-terminus chemokine sequences with subsequent modifications such as truncations or elongations. In this review, we present a glimpse of the different pharmacological actions reported for CDP and our current understanding regarding the potential use of CDP alone or as part of the novel therapies proposed in the treatment of microbial infections and cancer. Twit Text FOAVip Chemokine-Derived Peptides: Novel Antimicrobial and Antineoplasic Agents ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=26062132 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26062132 #FOAvip English Wikipedia <ref>{{Cite pmid|26062132}}</ref> Chemokine-Derived Peptides: Novel Antimicrobial and Antineoplasic Agents #MMPMID26062132 Valdivia-Silva J; Medina-Tamayo J; Garcia-Zepeda EA Int J Mol Sci 2015[Jun]; 16 (6): 12958-85 PMID26062132show ga Chemokines are a burgeoning family of chemotactic cytokines displaying a broad array of functions such as regulation of homeostatic leukocyte traffic and development, as well as activating the innate immune system. Their role in controlling early and late inflammatory stages is now well recognized. An improper balance either in chemokine synthesis or chemokine receptor expression contributes to various pathological disorders making chemokines and their receptors a useful therapeutic target. Research in this area is progressing rapidly, and development of novel agents based on chemokine/chemokine receptors antagonist functions are emerging as attractive alternative drugs. Some of these novel agents include generation of chemokine-derived peptides (CDP) with potential agonist and antagonist effects on inflammation, cancer and against bacterial infections. CDP have been generated mainly from N- and C-terminus chemokine sequences with subsequent modifications such as truncations or elongations. In this review, we present a glimpse of the different pharmacological actions reported for CDP and our current understanding regarding the potential use of CDP alone or as part of the novel therapies proposed in the treatment of microbial infections and cancer. äChemokine-Derived Peptides: Novel Antimicrobial and Antineoplasic Agen(epmc).pdf DeepDyve Pubget Overpricing