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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Nucl+Cardiol
2015 ; 22
(2
): 229-45
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Myocardial viability as integral part of the diagnostic and therapeutic approach
to ischemic heart failure
#MMPMID25733105
Bax JJ
; Delgado V
J Nucl Cardiol
2015[Apr]; 22
(2
): 229-45
PMID25733105
show ga
Chronic heart failure is a major public-health problem with a high prevalence,
complex treatment, and high mortality. A careful and comprehensive analysis is
needed to provide optimal (and personalized) therapy to heart failure patients.
The main 4 non-invasive imaging techniques (echocardiography, magnetic resonance
imaging, multi-detector-computed tomography, and nuclear imaging) provide
information on cardiovascular anatomy and function, which form the basis of the
assessment of the pathophysiology underlying heart failure. The selection of
imaging modalities depends on the information that is needed for the clinical
management of the patients: (1) underlying etiology (ischemic vs non-ischemic);
(2) in ischemic patients, need for revascularization should be evaluated
(myocardial ischemia/viability?); (3) left ventricular function and shape
assessment; (4) presence of significant secondary mitral regurgitation; (5)
device therapy with cardiac resynchronization therapy and/or implantable cardiac
defibrillator (risk of sudden cardiac death). This review is dedicated to
assessment of myocardial viability, however "isolated assessment of myocardial
viability" may be clinically not meaningful and should be considered among all
those different variables. This complete information will enable personalized
treatment of the patient with ischemic heart failure.
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