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10.1038/nrm2902

http://scihub22266oqcxt.onion/10.1038/nrm2902
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C4489880!4489880!20461097
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suck abstract from ncbi


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pmid20461097      Nat+Rev+Mol+Cell+Biol 2010 ; 11 (6): 404-13
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  • When pathways collide: collaboration and connivance among signaling proteins in development #MMPMID20461097
  • McNeill H; Woodgett JR
  • Nat Rev Mol Cell Biol 2010[Jun]; 11 (6): 404-13 PMID20461097show ga
  • Signal transduction pathways interact at various levels in defining tissue morphology, size and differentiation during development. Understanding of the mechanisms by which these pathways collude has been greatly enhanced by recent insights into how shared components are independently regulated and how the activity of one system is contextualized by others. Traditionally, the components of signalling pathways have been assumed to show pathway fidelity and to act with a high degree of autonomy. However, as illustrated by the Wnt and Hippo pathways, there is increasing evidence that components are often shared between multiple pathways and other components talk to each other through multiple mechanisms.
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