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10.3390/nu7065020

http://scihub22266oqcxt.onion/10.3390/nu7065020
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C4488829!4488829!26102214
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suck abstract from ncbi

pmid26102214      Nutrients 2015 ; 7 (6): 5020-50
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  • Mechanistic Effects of Calcitriol in Cancer Biology #MMPMID26102214
  • Díaz L; Díaz-Muñoz M; García-Gaytán AC; Méndez I
  • Nutrients 2015[Jun]; 7 (6): 5020-50 PMID26102214show ga
  • Besides its classical biological effects on calcium and phosphorus homeostasis, calcitriol, the active vitamin D metabolite, has a broad variety of actions including anticancer effects that are mediated either transcriptionally and/or via non-genomic pathways. In the context of cancer, calcitriol regulates the cell cycle, induces apoptosis, promotes cell differentiation and acts as anti-inflammatory factor within the tumor microenvironment. In this review, we address the different mechanisms of action involved in the antineoplastic effects of calcitriol.
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