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10.3390/toxins7061882

http://scihub22266oqcxt.onion/10.3390/toxins7061882
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C4488680!4488680!26035487
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suck abstract from ncbi


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pmid26035487      Toxins+(Basel) 2015 ; 7 (6): 1882-916
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  • Treatment of Gastrointestinal Sphincters Spasms with Botulinum Toxin A #MMPMID26035487
  • Brisinda G; Sivestrini N; Bianco G; Maria G
  • Toxins (Basel) 2015[Jun]; 7 (6): 1882-916 PMID26035487show ga
  • Botulinum toxin A inhibits neuromuscular transmission. It has become a drug with many indications. The range of clinical applications has grown to encompass several neurological and non-neurological conditions. One of the most recent achievements in the field is the observation that botulinum toxin A provides benefit in diseases of the gastrointestinal tract. Although toxin blocks cholinergic nerve endings in the autonomic nervous system, it has also been shown that it does not block non-adrenergic non-cholinergic responses mediated by nitric oxide. This has promoted further interest in using botulinum toxin A as a treatment for overactive smooth muscles and sphincters. The introduction of this therapy has made the treatment of several clinical conditions easier, in the outpatient setting, at a lower cost and without permanent complications. This review presents current data on the use of botulinum toxin A in the treatment of pathological conditions of the gastrointestinal tract.
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