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10.1186/s13054-015-0963-0

http://scihub22266oqcxt.onion/10.1186/s13054-015-0963-0
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C4488122!4488122!26070308
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suck abstract from ncbi


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pmid26070308      Crit+Care 2015 ; 19 (1): ä
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  • Effects of fluid administration on renal perfusion in critically ill patients #MMPMID26070308
  • Moussa MD; Scolletta S; Fagnoul D; Pasquier P; Brasseur A; Taccone FS; Vincent JL; De Backer D
  • Crit Care 2015[]; 19 (1): ä PMID26070308show ga
  • Introduction: Fluid administration is a first-line therapy for acute kidney injury associated with circulatory failure. Although aimed at increasing renal perfusion in these patients, this intervention may improve systemic hemodynamics without necessarily ameliorating intrarenal flow distribution or urine output. We used Doppler techniques to investigate the effects of fluid administration on intrarenal hemodynamics and the relationship between changes in renal hemodynamics and urine output. We hypothesized that, compared to systemic hemodynamic variables, changes in renal hemodynamics would better predict increase in urine output after fluid therapy. Methods: We measured systemic hemodynamic variables and performed renal interlobar artery Doppler on both kidneys before and after volume expansion in 49 adult patients with acute circulatory failure. We measured systolic and diastolic velocities and computed the resistivity index (RI). We recorded urine output for 3 h before and after the fluid challenge. Results: Fluid administration resulted in a small but consistent decrease in RI (from 0.73?±?0.09 to 0.71?±?0.09, p?
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