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10.1007/s00109-009-0557-x http://scihub22266oqcxt.onion/10.1007/s00109-009-0557-x C4487619!4487619!19898768     free     free     free       J+Mol+Med+(Berl) 2010 ; 88 (2): 97-102 Nephropedia Template TP {{tp|p=19898768|t=2010. The pneumococcus: why a commensal misbehaves |pdf=|usr=}}{{19898768}} gab.com Text The pneumococcus: why a commensal misbehaves JO: J Mol Med (Berl) http://www.kidney.de/pget.php?&tw=1&pmid=19898768 #FOAvip Several characteristics of Streptococcus pneumoniae (pneumococcus) combine to make it a particularly problematic pathogen. Firstly, the pneumococcus has the capacity to cause disease through the expression of virulence factors such as its polysaccharide capsule and pore-forming toxin. In addition, the pneumococcus is highly adaptable as demonstrated by its ability to acquire and disseminate resistance to multiple antibiotics. Although the pneumococcus is a major cause of disease, the organism is most commonly an ?asymptomatic? colonizer of its human host (the carrier state), with transmission occurring exclusively from this reservoir of commensal organisms. Thus, it is unclear how the organism?s virulence and adaptability promote its persistence or host to host spread during its carrier state. This review summarizes current understanding of how these characteristics may contribute to the commensal lifestyle of the pneumococcus. Twit Text FOAVip The pneumococcus: why a commensal misbehaves ????J Mol Med (Berl) http://www.kidney.de/pget.php?&tw=1&pmid=19898768 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=19898768 #FOAvip English Wikipedia <ref>{{Cite pmid|19898768}}</ref> The pneumococcus: why a commensal misbehaves #MMPMID19898768 Weiser JN J Mol Med (Berl) 2010[Feb]; 88 (2): 97-102 PMID19898768show ga Several characteristics of Streptococcus pneumoniae (pneumococcus) combine to make it a particularly problematic pathogen. Firstly, the pneumococcus has the capacity to cause disease through the expression of virulence factors such as its polysaccharide capsule and pore-forming toxin. In addition, the pneumococcus is highly adaptable as demonstrated by its ability to acquire and disseminate resistance to multiple antibiotics. Although the pneumococcus is a major cause of disease, the organism is most commonly an ?asymptomatic? colonizer of its human host (the carrier state), with transmission occurring exclusively from this reservoir of commensal organisms. Thus, it is unclear how the organism?s virulence and adaptability promote its persistence or host to host spread during its carrier state. This review summarizes current understanding of how these characteristics may contribute to the commensal lifestyle of the pneumococcus. äThe pneumococcus: why a commensal misbehaves (epmc).pdf DeepDyve Pubget Overpricing