Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1038/srep11916 http://scihub22266oqcxt.onion/10.1038/srep11916 C4487240!4487240!26132639     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2015 ; 5 (ä): ä Nephropedia Template TP {{tp|p=26132639|t=2015. Chromosome Scaffold is a Double-Stranded Assembly of Scaffold Proteins |pdf=|usr=}}{{26132639}} gab.com Text Chromosome Scaffold is a Double-Stranded Assembly of Scaffold Proteins JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26132639 #FOAvip Chromosome higher order structure has been an enigma for over a century. The most important structural finding has been the presence of a chromosome scaffold composed of non-histone proteins; so-called scaffold proteins. However, the organization and function of the scaffold are still controversial. Here, we use three dimensional-structured illumination microscopy (3D-SIM) and focused ion beam/scanning electron microscopy (FIB/SEM) to reveal the axial distributions of scaffold proteins in metaphase chromosomes comprising two strands. We also find that scaffold protein can adaptably recover its original localization after chromosome reversion in the presence of cations. This reversion to the original morphology underscores the role of the scaffold for intrinsic structural integrity of chromosomes. We therefore propose a new structural model of the chromosome scaffold that includes twisted double strands, consistent with the physical properties of chromosomal bending flexibility and rigidity. Our model provides new insights into chromosome higher order structure. Twit Text FOAVip Chromosome Scaffold is a Double-Stranded Assembly of Scaffold Proteins ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=26132639 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26132639 #FOAvip English Wikipedia <ref>{{Cite pmid|26132639}}</ref> Chromosome Scaffold is a Double-Stranded Assembly of Scaffold Proteins #MMPMID26132639 Poonperm R; Takata H; Hamano T; Matsuda A; Uchiyama S; Hiraoka Y; Fukui K Sci Rep 2015[]; 5 (ä): ä PMID26132639show ga Chromosome higher order structure has been an enigma for over a century. The most important structural finding has been the presence of a chromosome scaffold composed of non-histone proteins; so-called scaffold proteins. However, the organization and function of the scaffold are still controversial. Here, we use three dimensional-structured illumination microscopy (3D-SIM) and focused ion beam/scanning electron microscopy (FIB/SEM) to reveal the axial distributions of scaffold proteins in metaphase chromosomes comprising two strands. We also find that scaffold protein can adaptably recover its original localization after chromosome reversion in the presence of cations. This reversion to the original morphology underscores the role of the scaffold for intrinsic structural integrity of chromosomes. We therefore propose a new structural model of the chromosome scaffold that includes twisted double strands, consistent with the physical properties of chromosomal bending flexibility and rigidity. Our model provides new insights into chromosome higher order structure. äChromosome Scaffold is a Double-Stranded Assembly of Scaffold Proteins(epmc).pdf DeepDyve Pubget Overpricing