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10.1002/jbio.201300031 http://scihub22266oqcxt.onion/10.1002/jbio.201300031 C4486077!4486077!23674234     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Biophotonics 2014 ; 7 (ä): 9-22 Nephropedia Template TP {{tp|p=23674234|t=2014. Coherent anti-Stokes Raman scattering microscopy: overcoming technical barriers for clinical translation |pdf=|usr=}}{{23674234}} gab.com Text Coherent anti-Stokes Raman scattering microscopy: overcoming technical barriers for clinical translation JO: J Biophotonics http://www.kidney.de/pget.php?&tw=1&pmid=23674234 #FOAvip Clinical translation of coherent anti-Stokes Raman scattering microscopy is of great interest because of the advantages of noninvasive label-free imaging, high sensitivity, and chemical specificity. For this to happen, we have identified and review the technical barriers that must be overcome. Prior investigations have developed advanced techniques (features), each of which can be used to effectively overcome one particular technical barrier. However, the implementation of one or a small number of these advanced features in previous attempts for clinical translation has often introduced more tradeoffs than benefits. In this review, we outline a strategy that would integrate multiple advanced features to overcome all the technical barriers simultaneously, effectively reduce tradeoffs, and synergistically optimize CARS microscopy for clinical translation. The operation of the envisioned system incorporates coherent Raman micro-spectroscopy for identifying vibrational biomolecular markers of disease and single-frequency (or hyperspectral) Raman imaging of these specific biomarkers for real-time in vivo diagnostics and monitoring.An optimal scheme of clinical CARS micro-spectroscopy for thin ex vivo tissues. Twit Text FOAVip Coherent anti-Stokes Raman scattering microscopy: overcoming technical barriers for clinical translation ????J Biophotonics http://www.kidney.de/pget.php?&tw=1&pmid=23674234 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23674234 #FOAvip English Wikipedia <ref>{{Cite pmid|23674234}}</ref> Coherent anti-Stokes Raman scattering microscopy: overcoming technical barriers for clinical translation #MMPMID23674234 Tu H; Boppart SA J Biophotonics 2014[Jan]; 7 (ä): 9-22 PMID23674234show ga Clinical translation of coherent anti-Stokes Raman scattering microscopy is of great interest because of the advantages of noninvasive label-free imaging, high sensitivity, and chemical specificity. For this to happen, we have identified and review the technical barriers that must be overcome. Prior investigations have developed advanced techniques (features), each of which can be used to effectively overcome one particular technical barrier. However, the implementation of one or a small number of these advanced features in previous attempts for clinical translation has often introduced more tradeoffs than benefits. In this review, we outline a strategy that would integrate multiple advanced features to overcome all the technical barriers simultaneously, effectively reduce tradeoffs, and synergistically optimize CARS microscopy for clinical translation. The operation of the envisioned system incorporates coherent Raman micro-spectroscopy for identifying vibrational biomolecular markers of disease and single-frequency (or hyperspectral) Raman imaging of these specific biomarkers for real-time in vivo diagnostics and monitoring.An optimal scheme of clinical CARS micro-spectroscopy for thin ex vivo tissues. äCoherent anti-Stokes Raman scattering microscopy: overcoming technical(epmc).pdf DeepDyve Pubget Overpricing