Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1186/s12987-015-0012-z http://scihub22266oqcxt.onion/10.1186/s12987-015-0012-z C4485867!4485867!26118970     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Fluids+Barriers+CNS 2015 ; 12 (ä): ä Nephropedia Template TP {{tp|p=26118970|t=2015. A new glaucoma hypothesis: a role of glymphatic system dysfunction |pdf=|usr=}}{{26118970}} gab.com Text A new glaucoma hypothesis: a role of glymphatic system dysfunction JO: Fluids Barriers CNS http://www.kidney.de/pget.php?&tw=1&pmid=26118970 #FOAvip In a recent review article titled ?A new look at cerebrospinal fluid circulation?, Brinker et al. comprehensively described novel insights from molecular and cellular biology as well as neuroimaging research, which indicate that cerebrospinal fluid (CSF) physiology is much more complex than previously believed. The glymphatic system is a recently defined brain-wide paravascular pathway for CSF and interstitial fluid exchange that facilitates efficient clearance of interstitial solutes, including amyloid-?, from the brain. Although further studies are needed to substantiate the functional significance of the glymphatic concept, one implication is that glymphatic pathway dysfunction may contribute to the deficient amyloid-? clearance in Alzheimer?s disease. In this paper, we review several lines of evidence suggesting that the glymphatic system may also have potential clinical relevance for the understanding of glaucoma. As a clinically acceptable MRI-based approach to evaluate glymphatic pathway function in humans has recently been developed, a unique opportunity now exists to investigate whether suppression of the glymphatic system contributes to the development of glaucoma. The observation of a dysfunctional glymphatic system in patients with glaucoma would provide support for the hypothesis recently proposed by our group that CSF circulatory dysfunction may play a contributory role in the pathogenesis of glaucomatous damage. This would suggest a new hypothesis for glaucoma, which, just like Alzheimer?s disease, might be considered then as an imbalance between production and clearance of neurotoxins, including amyloid-?. Twit Text FOAVip A new glaucoma hypothesis: a role of glymphatic system dysfunction ????Fluids Barriers CNS http://www.kidney.de/pget.php?&tw=1&pmid=26118970 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26118970 #FOAvip English Wikipedia <ref>{{Cite pmid|26118970}}</ref> A new glaucoma hypothesis: a role of glymphatic system dysfunction #MMPMID26118970 Wostyn P; Van Dam D; Audenaert K; Killer HE; De Deyn PP; De Groot V Fluids Barriers CNS 2015[]; 12 (ä): ä PMID26118970show ga In a recent review article titled ?A new look at cerebrospinal fluid circulation?, Brinker et al. comprehensively described novel insights from molecular and cellular biology as well as neuroimaging research, which indicate that cerebrospinal fluid (CSF) physiology is much more complex than previously believed. The glymphatic system is a recently defined brain-wide paravascular pathway for CSF and interstitial fluid exchange that facilitates efficient clearance of interstitial solutes, including amyloid-?, from the brain. Although further studies are needed to substantiate the functional significance of the glymphatic concept, one implication is that glymphatic pathway dysfunction may contribute to the deficient amyloid-? clearance in Alzheimer?s disease. In this paper, we review several lines of evidence suggesting that the glymphatic system may also have potential clinical relevance for the understanding of glaucoma. As a clinically acceptable MRI-based approach to evaluate glymphatic pathway function in humans has recently been developed, a unique opportunity now exists to investigate whether suppression of the glymphatic system contributes to the development of glaucoma. The observation of a dysfunctional glymphatic system in patients with glaucoma would provide support for the hypothesis recently proposed by our group that CSF circulatory dysfunction may play a contributory role in the pathogenesis of glaucomatous damage. This would suggest a new hypothesis for glaucoma, which, just like Alzheimer?s disease, might be considered then as an imbalance between production and clearance of neurotoxins, including amyloid-?. äA new glaucoma hypothesis: a role of glymphatic system dysfunction (epmc).pdf DeepDyve Pubget Overpricing