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10.1080/2162402X.2015.1009288

http://scihub22266oqcxt.onion/10.1080/2162402X.2015.1009288
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suck abstract from ncbi


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pmid26155429
      Oncoimmunology 2015 ; 4 (6 ): e1009288
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  • Implications of understanding the signaling, cellular, and cytotoxic mechanisms afforded by afucosylated antibodies #MMPMID26155429
  • Liu SD ; Lowe JB
  • Oncoimmunology 2015[Jun]; 4 (6 ): e1009288 PMID26155429 show ga
  • Afucosylated antibodies potentiate natural killer (NK) cell-mediated antibody-dependent cellular cytotoxicity (ADCC) by enhancing signaling pathways and cellular processes, which in turn, increases cytotoxic potential. Importantly, a better understanding of these processes and properties will aid in exploiting them to help design therapeutic antibodies and strategies that may be of the greatest benefit to patients.
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