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10.1080/2162402X.2015.1011524

http://scihub22266oqcxt.onion/10.1080/2162402X.2015.1011524
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C4485778!4485778!26140234
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suck abstract from ncbi


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pmid26140234      Oncoimmunology 2015 ; 4 (7): ä
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  • Depletion of regulatory T cells by targeting CC chemokine receptor type 4 with mogamulizumab #MMPMID26140234
  • Ni X; Langridge T; Duvic M
  • Oncoimmunology 2015[Jul]; 4 (7): ä PMID26140234show ga
  • The CC chemokine receptor 4 (CCR4) is highly expressed on type 2 helper T cells and regulatory T (Treg) cells. Mogamulizumab, an anti-CCR4 antibody, reduces the numbers of CCR4+ malignant T cells and CCR4+ Treg cells in cutaneous T-cell lymphoma. Depleting Treg cells by targeting CCR4 has great potential in cancer immunotherapies.
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