Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1517/14728222.2015.1018181 http://scihub22266oqcxt.onion/10.1517/14728222.2015.1018181 C4484771!4484771!25768836     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Expert+Opin+Ther+Targets 2015 ; 19 (6): 835-47 Nephropedia Template TP {{tp|p=25768836|t=2015. Targeting the thyroid-stimulating hormone receptor with small molecule ligands and antibodies |pdf=|usr=}}{{25768836}} gab.com Text Targeting the thyroid-stimulating hormone receptor with small molecule ligands and antibodies JO: Expert Opin Ther Targets http://www.kidney.de/pget.php?&tw=1&pmid=25768836 #FOAvip Introduction: The thyroid-stimulating hormone receptor (TSHR) is the essential molecule for thyroid growth and thyroid hormone production. Since it is also a key autoantigen in Graves? disease and is involved in thyroid cancer pathophysiology, the targeting of the TSHR offers a logical model for disease control. Areas covered: We review the structure and function of the TSHR and the progress in both small molecule ligands and TSHR antibodies for their therapeutic potential. Expert opinion: Stabilization of a preferential conformation for the TSHR by allosteric ligands and TSHR antibodies with selective modulation of the signaling pathways is now possible. These tools may be the next generation of therapeutics for controlling the pathophysiological consequences mediated by the effects of the TSHR in the thyroid and other extrathyroidal tissues. Twit Text FOAVip Targeting the thyroid-stimulating hormone receptor with small molecule ligands and antibodies ????Expert Opin Ther Targets http://www.kidney.de/pget.php?&tw=1&pmid=25768836 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25768836 #FOAvip English Wikipedia <ref>{{Cite pmid|25768836}}</ref> Targeting the thyroid-stimulating hormone receptor with small molecule ligands and antibodies #MMPMID25768836 Davies TF; Latif R Expert Opin Ther Targets 2015[Jun]; 19 (6): 835-47 PMID25768836show ga Introduction: The thyroid-stimulating hormone receptor (TSHR) is the essential molecule for thyroid growth and thyroid hormone production. Since it is also a key autoantigen in Graves? disease and is involved in thyroid cancer pathophysiology, the targeting of the TSHR offers a logical model for disease control. Areas covered: We review the structure and function of the TSHR and the progress in both small molecule ligands and TSHR antibodies for their therapeutic potential. Expert opinion: Stabilization of a preferential conformation for the TSHR by allosteric ligands and TSHR antibodies with selective modulation of the signaling pathways is now possible. These tools may be the next generation of therapeutics for controlling the pathophysiological consequences mediated by the effects of the TSHR in the thyroid and other extrathyroidal tissues. äTargeting the thyroid-stimulating hormone receptor with small molecule(epmc).pdf DeepDyve Pubget Overpricing