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10.1101/gr.192278.115 http://scihub22266oqcxt.onion/10.1101/gr.192278.115 C4484390!4484390!25953952     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Genome+Res 2015 ; 25 (7): 927-36 Nephropedia Template TP {{tp|p=25953952|t=2015. The landscape of genomic imprinting across diverse adult human tissues |pdf=|usr=}}{{25953952}} gab.com Text The landscape of genomic imprinting across diverse adult human tissues JO: Genome Res http://www.kidney.de/pget.php?&tw=1&pmid=25953952 #FOAvip Genomic imprinting is an important regulatory mechanism that silences one of the parental copies of a gene. To systematically characterize this phenomenon, we analyze tissue specificity of imprinting from allelic expression data in 1582 primary tissue samples from 178 individuals from the Genotype-Tissue Expression (GTEx) project. We characterize imprinting in 42 genes, including both novel and previously identified genes. Tissue specificity of imprinting is widespread, and gender-specific effects are revealed in a small number of genes in muscle with stronger imprinting in males. IGF2 shows maternal expression in the brain instead of the canonical paternal expression elsewhere. Imprinting appears to have only a subtle impact on tissue-specific expression levels, with genes lacking a systematic expression difference between tissues with imprinted and biallelic expression. In summary, our systematic characterization of imprinting in adult tissues highlights variation in imprinting between genes, individuals, and tissues. Twit Text FOAVip The landscape of genomic imprinting across diverse adult human tissues ????Genome Res http://www.kidney.de/pget.php?&tw=1&pmid=25953952 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25953952 #FOAvip English Wikipedia <ref>{{Cite pmid|25953952}}</ref> The landscape of genomic imprinting across diverse adult human tissues #MMPMID25953952 Baran Y; Subramaniam M; Biton A; Tukiainen T; Tsang EK; Rivas MA; Pirinen M; Gutierrez-Arcelus M; Smith KS; Kukurba KR; Zhang R; Eng C; Torgerson DG; Urbanek C; Li JB; Rodriguez-Santana JR; Burchard EG; Seibold MA; MacArthur DG; Montgomery SB; Zaitlen NA; Lappalainen T Genome Res 2015[Jul]; 25 (7): 927-36 PMID25953952show ga Genomic imprinting is an important regulatory mechanism that silences one of the parental copies of a gene. To systematically characterize this phenomenon, we analyze tissue specificity of imprinting from allelic expression data in 1582 primary tissue samples from 178 individuals from the Genotype-Tissue Expression (GTEx) project. We characterize imprinting in 42 genes, including both novel and previously identified genes. Tissue specificity of imprinting is widespread, and gender-specific effects are revealed in a small number of genes in muscle with stronger imprinting in males. IGF2 shows maternal expression in the brain instead of the canonical paternal expression elsewhere. Imprinting appears to have only a subtle impact on tissue-specific expression levels, with genes lacking a systematic expression difference between tissues with imprinted and biallelic expression. In summary, our systematic characterization of imprinting in adult tissues highlights variation in imprinting between genes, individuals, and tissues. äThe landscape of genomic imprinting across diverse adult human tissues(epmc).pdf DeepDyve Pubget Overpricing