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10.3389/fimmu.2015.00317 http://scihub22266oqcxt.onion/10.3389/fimmu.2015.00317 C4484229!4484229!26175731     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Immunol 2015 ; 6 (ä): ä Nephropedia Template TP {{tp|p=26175731|t=2015. Emerging and Novel Functions of Complement Protein C1q |pdf=|usr=}}{{26175731}} gab.com Text Emerging and Novel Functions of Complement Protein C1q JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26175731 #FOAvip Complement protein C1q, the recognition molecule of the classical pathway, performs a diverse range of complement and non-complement functions. It can bind various ligands derived from self, non-self, and altered self and modulate the functions of immune and non-immune cells including dendritic cells and microglia. C1q involvement in the clearance of apoptotic cells and subsequent B cell tolerance is more established now. Recent evidence appears to suggest that C1q plays an important role in pregnancy where its deficiency and dysregulation can have adverse effects, leading to preeclampsia, missed abortion, miscarriage or spontaneous loss, and various infections. C1q is also produced locally in the central nervous system, and has a protective role against pathogens and possible inflammatory functions while interacting with aggregated proteins leading to neurodegenerative diseases. C1q role in synaptic pruning, and thus CNS development, its anti-cancer effects as an immune surveillance molecule, and possibly in aging are currently areas of extensive research. Twit Text FOAVip Emerging and Novel Functions of Complement Protein C1q ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26175731 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26175731 #FOAvip English Wikipedia <ref>{{Cite pmid|26175731}}</ref> Emerging and Novel Functions of Complement Protein C1q #MMPMID26175731 Kouser L; Madhukaran SP; Shastri A; Saraon A; Ferluga J; Al-Mozaini M; Kishore U Front Immunol 2015[]; 6 (ä): ä PMID26175731show ga Complement protein C1q, the recognition molecule of the classical pathway, performs a diverse range of complement and non-complement functions. It can bind various ligands derived from self, non-self, and altered self and modulate the functions of immune and non-immune cells including dendritic cells and microglia. C1q involvement in the clearance of apoptotic cells and subsequent B cell tolerance is more established now. Recent evidence appears to suggest that C1q plays an important role in pregnancy where its deficiency and dysregulation can have adverse effects, leading to preeclampsia, missed abortion, miscarriage or spontaneous loss, and various infections. C1q is also produced locally in the central nervous system, and has a protective role against pathogens and possible inflammatory functions while interacting with aggregated proteins leading to neurodegenerative diseases. C1q role in synaptic pruning, and thus CNS development, its anti-cancer effects as an immune surveillance molecule, and possibly in aging are currently areas of extensive research. äEmerging and Novel Functions of Complement Protein C1q (epmc).pdf DeepDyve Pubget Overpricing