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10.1371/journal.pone.0131225 http://scihub22266oqcxt.onion/10.1371/journal.pone.0131225 C4482251!4482251!26110611     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       PLoS+One 2015 ; 10 (6): ä Nephropedia Template TP {{tp|p=26110611|t=2015. cir-ITCH Plays an Inhibitory Role in Colorectal Cancer by Regulating the Wnt/?-Catenin Pathway |pdf=|usr=}}{{26110611}} gab.com Text cir-ITCH Plays an Inhibitory Role in Colorectal Cancer by Regulating the Wnt/ -Catenin Pathway JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=26110611 #FOAvip Noncoding RNAs (ncRNAs) are the dominant product of eukaryotic transcription. These products range from short microRNAs (miRNAs) to long intergenic noncoding RNAs (lincRNAs). Circular RNAs composed of exonic sequences represent an understudied form of ncRNA that was discovered more than 20 years ago. Using a TaqMan-based reverse transcriptase polymerase chain reaction assay, we analyzed the relationship between cir-ITCH expression and colorectal cancer (CRC) in a total of 45 CRCs and paired adjacent non-tumor tissue samples. We found that cir-ITCH expression was typically down-regulated in CRC compared to the peritumoral tissue. This result, as well as several follow-up experiments, showed that cir-ITCH could increase the level of ITCH, which is involved in the inhibition of the Wnt/?-catenin pathway. Therefore, our results showed that cir-ITCH plays a role in CRC by regulating the Wnt/?-catenin pathway. Twit Text FOAVip cir-ITCH Plays an Inhibitory Role in Colorectal Cancer by Regulating the Wnt/ -Catenin Pathway ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=26110611 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26110611 #FOAvip English Wikipedia <ref>{{Cite pmid|26110611}}</ref> cir-ITCH Plays an Inhibitory Role in Colorectal Cancer by Regulating the Wnt/?-Catenin Pathway #MMPMID26110611 Huang G; Zhu H; Shi Y; Wu W; Cai H; Chen X PLoS One 2015[]; 10 (6): ä PMID26110611show ga Noncoding RNAs (ncRNAs) are the dominant product of eukaryotic transcription. These products range from short microRNAs (miRNAs) to long intergenic noncoding RNAs (lincRNAs). Circular RNAs composed of exonic sequences represent an understudied form of ncRNA that was discovered more than 20 years ago. Using a TaqMan-based reverse transcriptase polymerase chain reaction assay, we analyzed the relationship between cir-ITCH expression and colorectal cancer (CRC) in a total of 45 CRCs and paired adjacent non-tumor tissue samples. We found that cir-ITCH expression was typically down-regulated in CRC compared to the peritumoral tissue. This result, as well as several follow-up experiments, showed that cir-ITCH could increase the level of ITCH, which is involved in the inhibition of the Wnt/?-catenin pathway. Therefore, our results showed that cir-ITCH plays a role in CRC by regulating the Wnt/?-catenin pathway. äcir-ITCH Plays an Inhibitory Role in Colorectal Cancer by Regulating t(epmc).pdf DeepDyve Pubget Overpricing