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10.1186/s13104-015-1255-0 http://scihub22266oqcxt.onion/10.1186/s13104-015-1255-0 C4482035!4482035 !26112053     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26112053 &cmd=llinks): Failed to open stream: HTTP request failed! 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A series of patients with minimal change nephropathy treated with rituximab during adolescence and adulthood |pdf=|usr=}}{{26112053 }} gab.com Text A series of patients with minimal change nephropathy treated with rituximab during adolescence and adulthood JO: BMC Res Notes http://www.kidney.de/pget.php?&tw=1&pmid=26112053 #FOAvip BACKGROUND: The treatment of immune suppression dependent minimal change nephropathy (MCN) can be challenging and frequently leads to serious complications. In paediatric patients, successful treatment with rituximab is described in steroid-dependent MCN. There is limited information about the potential efficacy of rituximab for the treatment of MCN in adults and adolescence. We describe our experience with rituximab in adolescent and adult patients with immune suppression dependent MCN. RESULTS: Ten adolescents and adults with immune suppression dependent MCN and therapy related complications were treated with rituximab. At a mean age of 26 years, about 10.5 years after first presentation, they received two doses of rituximab (375 mg/m(2)). Maintenance immunosuppressive medication was stopped. After a mean follow-up of 43 months, three patients had four relapses. Three relapses were successfully retreated with rituximab again, after induction therapy with 60 mg prednisone per day. Rituximab was well tolerated and no infectious complications were recorded. CONCLUSION: Treatment with rituximab induces a long-term remission of immune suppression dependent MCN in adolescents and adults. A timely treatment with rituximab could be considered to limit side effects of immunosuppressive medication. Twit Text FOAVip A series of patients with minimal change nephropathy treated with rituximab during adolescence and adulthood ????BMC Res Notes http://www.kidney.de/pget.php?&tw=1&pmid=26112053 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26112053 #FOAvip English Wikipedia <ref>{{Cite pmid|26112053 }}</ref> A series of patients with minimal change nephropathy treated with rituximab during adolescence and adulthood #MMPMID26112053 Dekkers MJ ; Groothoff JW ; Zietse R ; Betjes MG BMC Res Notes 2015[Jun]; 8 (ä): 266 PMID26112053 show ga BACKGROUND: The treatment of immune suppression dependent minimal change nephropathy (MCN) can be challenging and frequently leads to serious complications. In paediatric patients, successful treatment with rituximab is described in steroid-dependent MCN. There is limited information about the potential efficacy of rituximab for the treatment of MCN in adults and adolescence. We describe our experience with rituximab in adolescent and adult patients with immune suppression dependent MCN. RESULTS: Ten adolescents and adults with immune suppression dependent MCN and therapy related complications were treated with rituximab. At a mean age of 26 years, about 10.5 years after first presentation, they received two doses of rituximab (375 mg/m(2)). Maintenance immunosuppressive medication was stopped. After a mean follow-up of 43 months, three patients had four relapses. Three relapses were successfully retreated with rituximab again, after induction therapy with 60 mg prednisone per day. Rituximab was well tolerated and no infectious complications were recorded. CONCLUSION: Treatment with rituximab induces a long-term remission of immune suppression dependent MCN in adolescents and adults. A timely treatment with rituximab could be considered to limit side effects of immunosuppressive medication. |Adolescent [MESH] |Adult [MESH] |Drug Administration Schedule [MESH] |Female [MESH] |Humans [MESH] |Immunologic Factors/*therapeutic use [MESH] |Immunosuppression Therapy [MESH] |Induction Chemotherapy [MESH] |Kidney/drug effects/immunology/pathology [MESH] |Male [MESH] |Middle Aged [MESH] |Nephrosis, Lipoid/*drug therapy/immunology/pathology [MESH] |Prednisone/*therapeutic use [MESH] |Recurrence [MESH] |Remission Induction [MESH] |Retrospective Studies [MESH] |Rituximab/*therapeutic use [MESH]A series of patients with minimal change nephropathy treated with ritu(epmc).pdf DeepDyve Pubget Overpricing