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10.1182/blood-2014-08-595470

http://scihub22266oqcxt.onion/10.1182/blood-2014-08-595470
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C4481596!4481596!25852057
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suck abstract from ncbi


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pmid25852057      Blood 2015 ; 125 (26): 4085-94
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  • Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease #MMPMID25852057
  • Flynn R; Allen JL; Luznik L; MacDonald KP; Paz K; Alexander KA; Vulic A; Du J; Panoskaltsis-Mortari A; Taylor PA; Poe JC; Serody JS; Murphy WJ; Hill GR; Maillard I; Koreth J; Cutler CS; Soiffer RJ; Antin JH; Ritz J; Chao NJ; Clynes RA; Sarantopoulos S; Blazar BR
  • Blood 2015[Jun]; 125 (26): 4085-94 PMID25852057show ga
  • Syk is required for increased B-cell activation and cGVHD generation and maintenance.The Syk inhibitor fostamatinib can treat murine cGVHD and increase human cGVHD B-cell death.
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