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10.1007/s00399-015-0360-z http://scihub22266oqcxt.onion/10.1007/s00399-015-0360-z C4480946!4480946!25750090     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Herzschrittmacherther+Elektrophysiol 2015 ; 26 (2): 148-54 Nephropedia Template TP {{tp|p=25750090|t=2015. One-year safety and quality of life outcomes in patients with atrial fibrillation on dronedarone: prospective, non-interventional study in German ambulatory care |pdf=|usr=}}{{25750090}} gab.com Text One-year safety and quality of life outcomes in patients with atrial fibrillation on dronedarone: prospective, non-interventional study in German ambulatory care JO: Herzschrittmacherther Elektrophysiol http://www.kidney.de/pget.php?&tw=1&pmid=25750090 #FOAvip Background and aims: The multichannel blocker dronedarone is currently indicated for the maintenance of sinus rhythm after successful cardioversion in adult clinically stable patients with paroxysmal or persistent atrial fibrillation (AF), with careful monitoring of cardiac, hepatic and renal function. We aimed to investigate patients? quality of life (QoL) and tolerability and effectiveness of dronedarone under real life conditions. Methods: In the 1-year prospective, non-interventional IMPULS study, 161 office-based cardiologists, general practitioners and internists throughout Germany documented 549 patients with AF who were currently or newly prescribed dronedarone (safety set, SS). Of those, 342 patients (full analysis set, FAS) provided data on QoL at baseline, 6 months and 12 months). Results: Mean age of patients was 67.6/66.3 years; 53.0?%/57.3?% were men (SS/FAS). AF type at inclusion in the SS/FAS was paroxysmal in 71.9?%/71.3?% and persistent in 26.0?%/26.6?% (missing in 2.0?%/2.0?%). The proportion of patients in sinus rhythm increased from 44.6?% at baseline to 70.2?% (SS). The mean value on the 100-point visual analogue scale (EuroQol EQ-5D) increased from 62.3?±?17.1 at baseline by 11.4?±?18.7 points (FAS, p<0.0001). The AF-QoL Psychological Domain improved from 44.6?±?22.6 at baseline by 16.0?±?23.5 points at 1 year (p<0.0001), the AF-QoL physical domain from 49.5?±?22.1 by 10.9?±?22.5 points (p<0.0001), and the AF-QoL sexual domain from 61.8?±?27.1 by 6.6?±?28.2 points (p<0.0001). In all, 136 patients (24.8?% of all patients in the safety set) had at least one adverse drug reaction (ADR) causally related to dronedarone. Conclusions: Various dimensions of quality of life of patients with AF were improved on dronedarone under clinical practice conditions. No previously unknown safety issues were noted. Twit Text FOAVip One-year safety and quality of life outcomes in patients with atrial fibrillation on dronedarone: prospective, non-interventional study in German ambulatory care ????Herzschrittmacherther Elektrophysiol http://www.kidney.de/pget.php?&tw=1&pmid=25750090 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25750090 #FOAvip English Wikipedia <ref>{{Cite pmid|25750090}}</ref> One-year safety and quality of life outcomes in patients with atrial fibrillation on dronedarone: prospective, non-interventional study in German ambulatory care #MMPMID25750090 Goette A; Benninger G; Pittrow D; Paar W; von Stritzky B; Bosch R Herzschrittmacherther Elektrophysiol 2015[]; 26 (2): 148-54 PMID25750090show ga Background and aims: The multichannel blocker dronedarone is currently indicated for the maintenance of sinus rhythm after successful cardioversion in adult clinically stable patients with paroxysmal or persistent atrial fibrillation (AF), with careful monitoring of cardiac, hepatic and renal function. We aimed to investigate patients? quality of life (QoL) and tolerability and effectiveness of dronedarone under real life conditions. Methods: In the 1-year prospective, non-interventional IMPULS study, 161 office-based cardiologists, general practitioners and internists throughout Germany documented 549 patients with AF who were currently or newly prescribed dronedarone (safety set, SS). Of those, 342 patients (full analysis set, FAS) provided data on QoL at baseline, 6 months and 12 months). Results: Mean age of patients was 67.6/66.3 years; 53.0?%/57.3?% were men (SS/FAS). AF type at inclusion in the SS/FAS was paroxysmal in 71.9?%/71.3?% and persistent in 26.0?%/26.6?% (missing in 2.0?%/2.0?%). The proportion of patients in sinus rhythm increased from 44.6?% at baseline to 70.2?% (SS). The mean value on the 100-point visual analogue scale (EuroQol EQ-5D) increased from 62.3?±?17.1 at baseline by 11.4?±?18.7 points (FAS, p<0.0001). The AF-QoL Psychological Domain improved from 44.6?±?22.6 at baseline by 16.0?±?23.5 points at 1 year (p<0.0001), the AF-QoL physical domain from 49.5?±?22.1 by 10.9?±?22.5 points (p<0.0001), and the AF-QoL sexual domain from 61.8?±?27.1 by 6.6?±?28.2 points (p<0.0001). In all, 136 patients (24.8?% of all patients in the safety set) had at least one adverse drug reaction (ADR) causally related to dronedarone. Conclusions: Various dimensions of quality of life of patients with AF were improved on dronedarone under clinical practice conditions. No previously unknown safety issues were noted. äOne-year safety and quality of life outcomes in patients with atrial f(epmc).pdf DeepDyve Pubget Overpricing