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2015 ; 6
(4
): 204-18
Nephropedia Template TP
gab.com Text
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English Wikipedia
P2Y12 antagonists in non-ST-segment elevation acute coronary syndromes: latest
evidence and optimal use
#MMPMID26137210
Norgard NB
; DiNicolantonio JJ
Ther Adv Chronic Dis
2015[Jul]; 6
(4
): 204-18
PMID26137210
show ga
Dual antiplatelet therapy (DAPT), which includes the combination of aspirin and a
P2Y12 platelet receptor inhibitor, is a well-established antiplatelet regimen in
the treatment of patients with non-ST-segment elevation acute coronary syndrome
(NSTE-ACS). Three P2Y12 inhibitor options (clopidogrel, prasugrel and ticagrelor)
are currently available, all having different efficacy and safety profiles along
with contrasting contraindications, special warnings and precautions for use.
This review compares and contrasts the unique P2Y12 antagonists in the NSTE-ACS
setting, covering the latest evidence and their optimal use.