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10.1007/s00345-015-1535-2

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suck abstract from ncbi


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pmid25786708
      World+J+Urol 2015 ; 33 (7 ): 937-44
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  • Vascular-targeted photodynamic therapy with TOOKAD® Soluble in localized prostate cancer: standardization of the procedure #MMPMID25786708
  • Azzouzi AR ; Lebdai S ; Benzaghou F ; Stief C
  • World J Urol 2015[Jul]; 33 (7 ): 937-44 PMID25786708 show ga
  • INTRODUCTION: Vascular-targeted photodynamic therapy with TOOKAD(®) Soluble is an innovative focal therapy procedure assessed in localized prostate cancer treatment. MATERIALS AND METHODS: This mini-invasive technique destroys targeted tissues using a photosensitizer [TOOKAD(®) Soluble (WST11), STEBA Biotech] activated by laser light in the presence of oxygen. Its application for prostate cancer requires intravenous infusion of TOOKAD(®) Soluble and the illumination of the targeted area by transperineal optical fibers inserted under trans-rectal ultrasound guidance under general anesthesia. CONCLUSION: Based on the experience gained through hundreds of procedures, we describe here the standardized technique of vascular-targeted photodynamic therapy with TOOKAD(®) Soluble defined during the phase II and III trials.
  • |Bacteriochlorophylls/*therapeutic use [MESH]
  • |Humans [MESH]
  • |Male [MESH]
  • |Photochemotherapy/*methods/*standards [MESH]
  • |Photosensitizing Agents/*therapeutic use [MESH]


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